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- W2488093722 abstract "A preventive effect of early human cytomegalovirus (HCMV) replication was evaluated in 136 non-Hodgkin lymphoma (NHL) patients with mature B-cell NHLs (n = 94), and mature T- and NK-cell NHLs (n = 42) after allogeneic stem cell transplantation (alloSCT). Most study-patients (85%) had received at least 2 cycles of chemotherapy and 60% had also received an autograft prior to alloSCT. First detection of CMV-replication by HCMV antigenemia/viremia was found at a median of day +33 after alloSCT. The cumulative incidence of relapse at 5 years after alloSCT was 38% (95% confidence interval [95%CI]: 26–49) in 82 patients without compared to 22% (95%CI: 8–37) in 54 patients with HCMV antigenemia/viremia (p = .013). A decreased relapse risk of HCMV replication was confirmed by multivariate analysis for HCMV antigenemia/viremia (Hazard ratio [HR]: 0.29, 95%CI: 0.11–0.76, p < .014). This report demonstrated a possible improvement of relapse incidence after replicative HCMV infection in patients with NHL after alloSCT." @default.
- W2488093722 created "2016-08-23" @default.
- W2488093722 creator A5041775689 @default.
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- W2488093722 date "2016-08-10" @default.
- W2488093722 modified "2023-10-12" @default.
- W2488093722 title "Early CMV-replication after allogeneic stem cell transplantation is associated with a reduced relapse risk in lymphoma" @default.
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- W2488093722 doi "https://doi.org/10.1080/10428194.2016.1217524" @default.
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