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- W2488145909 abstract "Abstract Background Crescentic glomeruli are the hallmark finding in rapidly progressive glomerulonephritis ( RPGN ) and are characterized by disruption and proliferation of the glomerular capsule and an influx of cells into Bowman's space. Pauci‐immune‐type RPGN is identified by a lack of immunoglobulins and immune complexes in the glomerular basement membrane. Methods Complete necropsy and histology were performed on the affected chimpanzee. Electron microscopy was performed on kidney sections. A search of the literature was performed to identify spontaneous RPGN in animals. Results We report a case of crescentic glomerulonephritis of the pauci‐immune‐type in a hepatitis C virus‐infected 28‐year‐old male chimpanzee ( Pan troglodytes ) who was humanely euthanized for a cardiac‐related decline in health. Conclusion To our knowledge, this is the first report describing pauci‐immune crescentic glomerulonephritis in a non‐human primate." @default.
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- W2488145909 date "2016-08-10" @default.
- W2488145909 modified "2023-10-03" @default.
- W2488145909 title "Pauci-immune glomerulonephritis in a captive chimpanzee (<i>Pan troglodytes</i> ), and a review of spontaneous cases in animals" @default.
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- W2488145909 doi "https://doi.org/10.1111/jmp.12233" @default.
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