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- W2488530792 abstract "Zebrafish are still a relatively new, but promising, model organism and increasingly used in behavioral studies. This chapter reviews some of the behavioral paradigms that show promise in behavioral neuroscience as it applies to pervasive developmental disorders (PDD) of the brain, such as autism. Predictive and high-throughput animal models of cognition and behavior are increasingly more important in translational neuroscience research and zebrafish could be an excellent tool in this area. The zebrafish’ complex behavioral repertoire, its size, relative low cost, short generation time, and high homology with higher vertebrates make it an excellent model organism. Rodents have traditionally been used to study complex cognitive phenotypes. However, it is particularly the physical features of zebrafish (small size, short generation time) that make it an appealing model to complement the progress made in the rodent literature. Taking into account that no single animal model can recapitulate all aspects of human behaviors impaired in pervasive brain disorders, using zebrafish to complement existing efforts using different models may open up new avenues of discovery not previously explored. While promising, zebrafish are a new model and many existing paradigms are being translated to the zebrafish larval and adult model. This chapter aims to discuss various important behavioral paradigms and how they relate to the study of PDDs." @default.
- W2488530792 created "2016-08-23" @default.
- W2488530792 creator A5026176392 @default.
- W2488530792 date "2014-12-22" @default.
- W2488530792 modified "2023-09-27" @default.
- W2488530792 title "Zebrafish Social Behavior Testing in Developmental Brain Disorders" @default.
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- W2488530792 doi "https://doi.org/10.1007/978-1-4939-2250-5_12" @default.
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