FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2488540797> ?p ?o ?g. }

• W2488540797 endingPage "69" @default.
• W2488540797 startingPage "69" @default.
• W2488540797 abstract "Coumestrol (Cou) is a plant-derived phytoestrogen that induces various pathologies in the female reproductive tract. Although effects of phytoestrogens on reproductive function in other species are well documented, their influence on progesterone (P4) and prostaglandin (PG) secretion in the mare is unknown. The aim of this study was to determine if Cou directly affects P4and PG concentrations (in vivo) and endometrial PG secretion (in vitro) in the mare. In experiment 1, the mares (n = 4) were fed for 14 days on a diet containing increasing proportions of alfalfa pellets (250 g–1 kg/day). An additional 4 mares were fed a standard diet (control group). Sequential blood samples were obtained for 8 h after feeding on Days 13 and 14 (1 kg/day alfalfa pellets). Feeding the mares alfalfa pellets up-regulated PGE2and 13,14-dihydro-15-ketoprostaglandin F2alpha(PGFM) and down-regulated P4in the blood plasma compared to those in the control group (P< 0.05). In experiment 2, epithelial and stromal cells were exposed to E2(10−9M) or Cou (10−8M) for 24 h. In the in vitro study, Cou increased PG secretion in epithelial and stromal cells (P< 0.05). In both types of endometrial cells, Cou up-regulated PTGS-2 protein expression (P< 0.05). Moreover, PGES and PGFS proteins were up-regulated by Cou in epithelial cells (P< 0.01). These results indicate that Cou can disturb reproductive function by affecting reproductive hormone secretion and altering the endometrial milieu through PG stimulation. Coumestrol therefore may impair physiologic regulation of the estrous cycle and early pregnancy." @default.
• W2488540797 created "2016-08-23" @default.
• W2488540797 creator A5010977039 @default.
• W2488540797 creator A5012506757 @default.
• W2488540797 creator A5026696311 @default.
• W2488540797 creator A5027531992 @default.
• W2488540797 creator A5029328986 @default.
• W2488540797 creator A5062141977 @default.
• W2488540797 creator A5070346443 @default.
• W2488540797 creator A5086091249 @default.
• W2488540797 date "2016-08-03" @default.
• W2488540797 modified "2023-10-16" @default.
• W2488540797 title "The Effect of Coumestrol on Progesterone and Prostaglandin Production in the Mare: In Vitro and In Vivo Studies" @default.
• W2488540797 cites W158972100 @default.
• W2488540797 cites W1974252659 @default.
• W2488540797 cites W1975165380 @default.
• W2488540797 cites W1982430348 @default.
• W2488540797 cites W1991448134 @default.
• W2488540797 cites W1992959059 @default.
• W2488540797 cites W1997479612 @default.
• W2488540797 cites W2015684119 @default.
• W2488540797 cites W2022151335 @default.
• W2488540797 cites W2022917798 @default.
• W2488540797 cites W2027349642 @default.
• W2488540797 cites W2045955842 @default.
• W2488540797 cites W2046829776 @default.
• W2488540797 cites W2047304664 @default.
• W2488540797 cites W2047415235 @default.
• W2488540797 cites W2048440094 @default.
• W2488540797 cites W2073373208 @default.
• W2488540797 cites W2073417234 @default.
• W2488540797 cites W2079259713 @default.
• W2488540797 cites W2082115843 @default.
• W2488540797 cites W2083767540 @default.
• W2488540797 cites W2086318102 @default.
• W2488540797 cites W2103311747 @default.
• W2488540797 cites W2112729261 @default.
• W2488540797 cites W2119048836 @default.
• W2488540797 cites W2121844441 @default.
• W2488540797 cites W2129789331 @default.
• W2488540797 cites W2137968666 @default.
• W2488540797 cites W2138435704 @default.
• W2488540797 cites W2154555026 @default.
• W2488540797 cites W2158452146 @default.
• W2488540797 cites W2181983966 @default.
• W2488540797 cites W2304910108 @default.
• W2488540797 cites W2314440494 @default.
• W2488540797 cites W2317363980 @default.
• W2488540797 cites W2339137474 @default.
• W2488540797 cites W250151107 @default.
• W2488540797 doi "https://doi.org/10.1095/biolreprod.116.138958" @default.
• W2488540797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27488032" @default.
• W2488540797 hasPublicationYear "2016" @default.
• W2488540797 type Work @default.
• W2488540797 sameAs 2488540797 @default.
• W2488540797 citedByCount "4" @default.
• W2488540797 countsByYear W24885407972017 @default.
• W2488540797 countsByYear W24885407972022 @default.
• W2488540797 countsByYear W24885407972023 @default.
• W2488540797 crossrefType "journal-article" @default.
• W2488540797 hasAuthorship W2488540797A5010977039 @default.
• W2488540797 hasAuthorship W2488540797A5012506757 @default.
• W2488540797 hasAuthorship W2488540797A5026696311 @default.
• W2488540797 hasAuthorship W2488540797A5027531992 @default.
• W2488540797 hasAuthorship W2488540797A5029328986 @default.
• W2488540797 hasAuthorship W2488540797A5062141977 @default.
• W2488540797 hasAuthorship W2488540797A5070346443 @default.
• W2488540797 hasAuthorship W2488540797A5086091249 @default.
• W2488540797 hasBestOaLocation W24885407971 @default.
• W2488540797 hasConcept C126322002 @default.
• W2488540797 hasConcept C134018914 @default.
• W2488540797 hasConcept C150903083 @default.
• W2488540797 hasConcept C16930146 @default.
• W2488540797 hasConcept C207001950 @default.
• W2488540797 hasConcept C2777164284 @default.
• W2488540797 hasConcept C2778270713 @default.
• W2488540797 hasConcept C2778355148 @default.
• W2488540797 hasConcept C2780664492 @default.
• W2488540797 hasConcept C49039625 @default.
• W2488540797 hasConcept C502942594 @default.
• W2488540797 hasConcept C71315377 @default.
• W2488540797 hasConcept C71924100 @default.
• W2488540797 hasConcept C86803240 @default.
• W2488540797 hasConceptScore W2488540797C126322002 @default.
• W2488540797 hasConceptScore W2488540797C134018914 @default.
• W2488540797 hasConceptScore W2488540797C150903083 @default.
• W2488540797 hasConceptScore W2488540797C16930146 @default.
• W2488540797 hasConceptScore W2488540797C207001950 @default.
• W2488540797 hasConceptScore W2488540797C2777164284 @default.
• W2488540797 hasConceptScore W2488540797C2778270713 @default.
• W2488540797 hasConceptScore W2488540797C2778355148 @default.
• W2488540797 hasConceptScore W2488540797C2780664492 @default.
• W2488540797 hasConceptScore W2488540797C49039625 @default.
• W2488540797 hasConceptScore W2488540797C502942594 @default.
• W2488540797 hasConceptScore W2488540797C71315377 @default.
• W2488540797 hasConceptScore W2488540797C71924100 @default.
• W2488540797 hasConceptScore W2488540797C86803240 @default.
• W2488540797 hasIssue "3" @default.

• next