FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2488602204> ?p ?o ?g. }

• W2488602204 endingPage "297" @default.
• W2488602204 startingPage "273" @default.
• W2488602204 abstract "Abasic sites in DNA arise from spontaneous damage and, if left unrepaired, contribute to mutations. Dedicated pathways have evolved to repair abasic DNA; however, the biological implications and cellular fate of RNA possessing these lesions are not well characterized. In this chapter, we review advances in the area of RNA depurination, which produces the dominant form of abasic RNA in vivo. We discuss the biochemistry of RNA depurination, the varied impacts of cellular and viral RNA depurination, and the numerous methods available for detecting abasic RNA. Given the abundance of RNA in cells and the relative stability of abasic RNA compared with DNA, depurinated RNA likely has physiological significance. Recent work suggests a link between RNA depurination and some age-related diseases as well as downstream signalling pathways that induce apoptosis. In addition, pathogens with RNA genomes are influenced by depurination. For example, abasic sites of HIV-1 RNA may contribute to adaptation by mutation and recombination. Therefore, effects of RNA depurination have medical relevance that warrants continued study." @default.
• W2488602204 created "2016-08-23" @default.
• W2488602204 creator A5002229751 @default.
• W2488602204 creator A5031852302 @default.
• W2488602204 creator A5087890722 @default.
• W2488602204 creator A5088602314 @default.
• W2488602204 date "2016-01-01" @default.
• W2488602204 modified "2023-09-23" @default.
• W2488602204 title "Effect of Depurination on Cellular and Viral RNA" @default.
• W2488602204 cites W101475269 @default.
• W2488602204 cites W1482431053 @default.
• W2488602204 cites W1549431764 @default.
• W2488602204 cites W1569531441 @default.
• W2488602204 cites W1577035491 @default.
• W2488602204 cites W1602417853 @default.
• W2488602204 cites W1964625667 @default.
• W2488602204 cites W1966206863 @default.
• W2488602204 cites W1966998631 @default.
• W2488602204 cites W1967396825 @default.
• W2488602204 cites W1967899016 @default.
• W2488602204 cites W1968938578 @default.
• W2488602204 cites W1970727027 @default.
• W2488602204 cites W1974292947 @default.
• W2488602204 cites W1977966257 @default.
• W2488602204 cites W1979048982 @default.
• W2488602204 cites W1979266902 @default.
• W2488602204 cites W1979472284 @default.
• W2488602204 cites W1984226439 @default.
• W2488602204 cites W1984228574 @default.
• W2488602204 cites W1984253264 @default.
• W2488602204 cites W1984786939 @default.
• W2488602204 cites W1985205864 @default.
• W2488602204 cites W1987128233 @default.
• W2488602204 cites W1988328659 @default.
• W2488602204 cites W1991620316 @default.
• W2488602204 cites W1991703715 @default.
• W2488602204 cites W1993435209 @default.
• W2488602204 cites W1993987952 @default.
• W2488602204 cites W1996040288 @default.
• W2488602204 cites W1998171008 @default.
• W2488602204 cites W1998955318 @default.
• W2488602204 cites W2001044345 @default.
• W2488602204 cites W2004738840 @default.
• W2488602204 cites W2007179145 @default.
• W2488602204 cites W2009109048 @default.
• W2488602204 cites W2018484218 @default.
• W2488602204 cites W2023351923 @default.
• W2488602204 cites W2023831963 @default.
• W2488602204 cites W2025046948 @default.
• W2488602204 cites W2025930859 @default.
• W2488602204 cites W2027340857 @default.
• W2488602204 cites W2028553114 @default.
• W2488602204 cites W2028976892 @default.
• W2488602204 cites W2029816142 @default.
• W2488602204 cites W2030475136 @default.
• W2488602204 cites W2032735163 @default.
• W2488602204 cites W2035762783 @default.
• W2488602204 cites W2037595703 @default.
• W2488602204 cites W2039290476 @default.
• W2488602204 cites W2039913172 @default.
• W2488602204 cites W2040302790 @default.
• W2488602204 cites W2046488868 @default.
• W2488602204 cites W2048646541 @default.
• W2488602204 cites W2051075314 @default.
• W2488602204 cites W2052551096 @default.
• W2488602204 cites W2055286910 @default.
• W2488602204 cites W2055546011 @default.
• W2488602204 cites W2056450889 @default.
• W2488602204 cites W2057283384 @default.
• W2488602204 cites W2068288879 @default.
• W2488602204 cites W2068409591 @default.
• W2488602204 cites W2069968653 @default.
• W2488602204 cites W2080872178 @default.
• W2488602204 cites W2081883768 @default.
• W2488602204 cites W2084391189 @default.
• W2488602204 cites W2084695608 @default.
• W2488602204 cites W2084855808 @default.
• W2488602204 cites W2085976991 @default.
• W2488602204 cites W2086616627 @default.
• W2488602204 cites W2091404872 @default.
• W2488602204 cites W2092525320 @default.
• W2488602204 cites W2095245152 @default.
• W2488602204 cites W2101319369 @default.
• W2488602204 cites W2104825395 @default.
• W2488602204 cites W2106435800 @default.
• W2488602204 cites W2108736984 @default.
• W2488602204 cites W2111252388 @default.
• W2488602204 cites W2112093431 @default.
• W2488602204 cites W2114847093 @default.
• W2488602204 cites W2120013569 @default.
• W2488602204 cites W2122406382 @default.
• W2488602204 cites W2122862521 @default.
• W2488602204 cites W2124095626 @default.
• W2488602204 cites W2126917185 @default.
• W2488602204 cites W2127242992 @default.
• W2488602204 cites W2137353179 @default.
• W2488602204 cites W2139725422 @default.
• W2488602204 cites W2140796894 @default.

• next