Matches in SemOpenAlex for { <https://semopenalex.org/work/W2488655901> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2488655901 abstract "Current treatment regimens with either long-term interferon (IFN) monotherapy or interferon-ribavirin combination achieve a sustained response of 6-21%. To improve the efficacy of IFN several strategies have been devised, including the use of higher doses of IFN, prolonged courses or pegylated IFN. Some recent reports have suggested that daily administration of IFN in the early phase of therapy (induction dose) may be more efficacious than the classic thrice-weekly regimen. There is no available data about the combination of induction dose regimen of IFN and ribavirin. Our objective was to evaluate prospectively the efficacy and safety of a 5mu IFN induction dose in combination with ribavirin in HCV patients. End treatment response (ETR) was 36.7% of the 30 patients included in the study, while 81.1% ofresponders could remain viral negative for one year after discontinuation of treatment (sustained response). Though responders had higher pretreatment levels of viraemia and ALT, it was still without statistical signficance. Also, there was no statistical histological difference between both groups. There was a significant correlation between response rate and post induction viraemia level (p < 0.05) but no similar relation to post-induction ALT level. We conclude that induction dose regimen seems to have no effect on ETR but may improve sustained response. Also, post-induction viral load level is a good predictor for both ET and sustained responses." @default.
- W2488655901 created "2016-08-23" @default.
- W2488655901 creator A5006861492 @default.
- W2488655901 creator A5022885300 @default.
- W2488655901 creator A5031755512 @default.
- W2488655901 creator A5037763123 @default.
- W2488655901 creator A5043306214 @default.
- W2488655901 creator A5070077987 @default.
- W2488655901 creator A5073311443 @default.
- W2488655901 date "2002-11-01" @default.
- W2488655901 modified "2023-09-27" @default.
- W2488655901 title "Evaluation of Loading Dose of IFN in HCV Patients: Prospective, Uncontrolled Study" @default.
- W2488655901 cites W1973950285 @default.
- W2488655901 cites W1981095040 @default.
- W2488655901 cites W1991378085 @default.
- W2488655901 cites W2001856916 @default.
- W2488655901 cites W2011488224 @default.
- W2488655901 cites W2034185999 @default.
- W2488655901 cites W2043144554 @default.
- W2488655901 cites W2043519223 @default.
- W2488655901 cites W2053100601 @default.
- W2488655901 cites W2069633422 @default.
- W2488655901 cites W2077511744 @default.
- W2488655901 cites W2079771726 @default.
- W2488655901 cites W2083205190 @default.
- W2488655901 cites W2116345541 @default.
- W2488655901 cites W2122494591 @default.
- W2488655901 cites W2129767605 @default.
- W2488655901 cites W2166971952 @default.
- W2488655901 cites W2167403799 @default.
- W2488655901 cites W2319055243 @default.
- W2488655901 cites W2415508537 @default.
- W2488655901 cites W1988514209 @default.
- W2488655901 doi "https://doi.org/10.5339/qmj.2002.2.19" @default.
- W2488655901 hasPublicationYear "2002" @default.
- W2488655901 type Work @default.
- W2488655901 sameAs 2488655901 @default.
- W2488655901 citedByCount "0" @default.
- W2488655901 crossrefType "journal-article" @default.
- W2488655901 hasAuthorship W2488655901A5006861492 @default.
- W2488655901 hasAuthorship W2488655901A5022885300 @default.
- W2488655901 hasAuthorship W2488655901A5031755512 @default.
- W2488655901 hasAuthorship W2488655901A5037763123 @default.
- W2488655901 hasAuthorship W2488655901A5043306214 @default.
- W2488655901 hasAuthorship W2488655901A5070077987 @default.
- W2488655901 hasAuthorship W2488655901A5073311443 @default.
- W2488655901 hasConcept C126322002 @default.
- W2488655901 hasConcept C142462285 @default.
- W2488655901 hasConcept C203014093 @default.
- W2488655901 hasConcept C2522874641 @default.
- W2488655901 hasConcept C2776178377 @default.
- W2488655901 hasConcept C2776999253 @default.
- W2488655901 hasConcept C2778715236 @default.
- W2488655901 hasConcept C2780040827 @default.
- W2488655901 hasConcept C2781413609 @default.
- W2488655901 hasConcept C3013748606 @default.
- W2488655901 hasConcept C3020491458 @default.
- W2488655901 hasConcept C71924100 @default.
- W2488655901 hasConcept C90924648 @default.
- W2488655901 hasConcept C98274493 @default.
- W2488655901 hasConceptScore W2488655901C126322002 @default.
- W2488655901 hasConceptScore W2488655901C142462285 @default.
- W2488655901 hasConceptScore W2488655901C203014093 @default.
- W2488655901 hasConceptScore W2488655901C2522874641 @default.
- W2488655901 hasConceptScore W2488655901C2776178377 @default.
- W2488655901 hasConceptScore W2488655901C2776999253 @default.
- W2488655901 hasConceptScore W2488655901C2778715236 @default.
- W2488655901 hasConceptScore W2488655901C2780040827 @default.
- W2488655901 hasConceptScore W2488655901C2781413609 @default.
- W2488655901 hasConceptScore W2488655901C3013748606 @default.
- W2488655901 hasConceptScore W2488655901C3020491458 @default.
- W2488655901 hasConceptScore W2488655901C71924100 @default.
- W2488655901 hasConceptScore W2488655901C90924648 @default.
- W2488655901 hasConceptScore W2488655901C98274493 @default.
- W2488655901 hasIssue "2" @default.
- W2488655901 hasLocation W24886559011 @default.
- W2488655901 hasOpenAccess W2488655901 @default.
- W2488655901 hasPrimaryLocation W24886559011 @default.
- W2488655901 hasRelatedWork W1970823932 @default.
- W2488655901 hasRelatedWork W1978094487 @default.
- W2488655901 hasRelatedWork W1981913416 @default.
- W2488655901 hasRelatedWork W1987157627 @default.
- W2488655901 hasRelatedWork W2071277949 @default.
- W2488655901 hasRelatedWork W2098357894 @default.
- W2488655901 hasRelatedWork W2416887822 @default.
- W2488655901 hasRelatedWork W2438653439 @default.
- W2488655901 hasRelatedWork W2488655901 @default.
- W2488655901 hasRelatedWork W3029429740 @default.
- W2488655901 hasVolume "2002" @default.
- W2488655901 isParatext "false" @default.
- W2488655901 isRetracted "false" @default.
- W2488655901 magId "2488655901" @default.
- W2488655901 workType "article" @default.