FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2488700650> ?p ?o ?g. }

• W2488700650 endingPage "e279" @default.
• W2488700650 startingPage "e278" @default.
• W2488700650 abstract "Objective: Treatment-related reductions in microalbuminuria (MAU) are associated with a reduced incidence of cardiovascular events and a reduction in progression to end-stage renal disease in hypertensive patients, but if reduction in MAU correlates with regression of left ventricular hypertrophy (LVH) is still insufficiently studied. Our goal was to assess changes in the level of microalbuminuria and its relationship with regression of LVH during antihypertensive treatment. Design and method: 443 patients with microalbuminuria and LVH were treated with losartan 50–100 mg plus hydrochlorothiazide 12.5–25 mg (219 patients) or amlodipine 5–10 mg o.i.d. (224 patients) during follow-up period of 12 months. Albumin-creatinine ratio was measured in the first morning void urine prior to treatment and 4 weeks after treatment. After 4 weeks of losartan-based combination therapy patients were divided according to reduction in albumin-creatinine ratio on 2 groups: <50% from baseline (1st group) and >50% from baseline (2nd group). Results: Reduction in albumin-creatinine ratio after 4 weeks of treatment in the 1st group was 28% (from 11.8 ± 7.3 to 8.4 ± 3.8 mg/mmol) (p > 0.05) and in the 2nd group was 71% (from 10.9 ± 4.2 to 3.2 ± 1.6 mg/mmol, p < 0.05). In the 1st group office systolic blood pressure (BP) decreased from 166 ± 4/91 ± 3 to 133 ± 3/79 ± 2 mmHg (p < 0.01) and in the 2nd group from 163 ± 5/93 ± 2 to 131 ± 4/80 ± 1 mmHg (p < 0.05), respectively. Decrease of LVMI was significantly higher after 1 year of treatment in the 2nd group as compared with the 1st group (-19.4 ± 4.1% vs -6.5 ± 3.2%, respectively (p < 0.01). In a multiple regression model, significant relationship between reduction in microalbuminuria and decrease of LVMI was found, independent of office systolic and diastolic BP changes, age and sex (p < 0.01). Conclusions: There is a strong relationship between reduction in albumin-creatinine ratio and regression of LVH in hypertensive patients. Reduction in microalbuminuria after 4 weeks of treatment predicts further regression of left ventricular hypertrophy in hypertensive patients." @default.
• W2488700650 created "2016-08-23" @default.
• W2488700650 creator A5000512651 @default.
• W2488700650 creator A5079199398 @default.
• W2488700650 date "2016-09-01" @default.
• W2488700650 modified "2023-09-27" @default.
• W2488700650 title "[PP.26.19] EFFECT OF LOSARTAN IN COMBINATION WITH AMLODIPINE OR HYDROCHLOROTHIAZIDE ON MICROALBUMINURIA PREDICTS REGRESSION OF LEFT VENTRICULAR HYPERTROPHY IN HYPERTENSIVE PATIENTS" @default.
• W2488700650 doi "https://doi.org/10.1097/01.hjh.0000492149.24335.78" @default.
• W2488700650 hasPublicationYear "2016" @default.
• W2488700650 type Work @default.
• W2488700650 sameAs 2488700650 @default.
• W2488700650 citedByCount "0" @default.
• W2488700650 crossrefType "journal-article" @default.
• W2488700650 hasAuthorship W2488700650A5000512651 @default.
• W2488700650 hasAuthorship W2488700650A5079199398 @default.
• W2488700650 hasConcept C126322002 @default.
• W2488700650 hasConcept C126894567 @default.
• W2488700650 hasConcept C134018914 @default.
• W2488700650 hasConcept C159641895 @default.
• W2488700650 hasConcept C164705383 @default.
• W2488700650 hasConcept C2776002628 @default.
• W2488700650 hasConcept C2776174234 @default.
• W2488700650 hasConcept C2779646130 @default.
• W2488700650 hasConcept C2779881121 @default.
• W2488700650 hasConcept C2780288358 @default.
• W2488700650 hasConcept C2780306776 @default.
• W2488700650 hasConcept C2780361556 @default.
• W2488700650 hasConcept C2781203188 @default.
• W2488700650 hasConcept C2908929049 @default.
• W2488700650 hasConcept C71924100 @default.
• W2488700650 hasConcept C84393581 @default.
• W2488700650 hasConceptScore W2488700650C126322002 @default.
• W2488700650 hasConceptScore W2488700650C126894567 @default.
• W2488700650 hasConceptScore W2488700650C134018914 @default.
• W2488700650 hasConceptScore W2488700650C159641895 @default.
• W2488700650 hasConceptScore W2488700650C164705383 @default.
• W2488700650 hasConceptScore W2488700650C2776002628 @default.
• W2488700650 hasConceptScore W2488700650C2776174234 @default.
• W2488700650 hasConceptScore W2488700650C2779646130 @default.
• W2488700650 hasConceptScore W2488700650C2779881121 @default.
• W2488700650 hasConceptScore W2488700650C2780288358 @default.
• W2488700650 hasConceptScore W2488700650C2780306776 @default.
• W2488700650 hasConceptScore W2488700650C2780361556 @default.
• W2488700650 hasConceptScore W2488700650C2781203188 @default.
• W2488700650 hasConceptScore W2488700650C2908929049 @default.
• W2488700650 hasConceptScore W2488700650C71924100 @default.
• W2488700650 hasConceptScore W2488700650C84393581 @default.
• W2488700650 hasIssue "Supplement 2" @default.
• W2488700650 hasLocation W24887006501 @default.
• W2488700650 hasOpenAccess W2488700650 @default.
• W2488700650 hasPrimaryLocation W24887006501 @default.
• W2488700650 hasRelatedWork W1992690695 @default.
• W2488700650 hasRelatedWork W2044482719 @default.
• W2488700650 hasRelatedWork W2092544422 @default.
• W2488700650 hasRelatedWork W2136910005 @default.
• W2488700650 hasRelatedWork W2353401203 @default.
• W2488700650 hasRelatedWork W2389874993 @default.
• W2488700650 hasRelatedWork W2488700650 @default.
• W2488700650 hasRelatedWork W2886085825 @default.
• W2488700650 hasRelatedWork W3119567526 @default.
• W2488700650 hasRelatedWork W656697013 @default.
• W2488700650 hasVolume "34" @default.
• W2488700650 isParatext "false" @default.
• W2488700650 isRetracted "false" @default.
• W2488700650 magId "2488700650" @default.
• W2488700650 workType "article" @default.