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- W2488734039 abstract "This chapter describes the tumor-associated antigens as expressions of chemically induced neoplasia and their involvement in tumor–host interactions. Studies were carried out to establish whether individually distinctive tumor-associated antigens were demonstrable by membrane immunofluorescence reactions with sera from syngenic rats immunized against transplanted sarcoma cells or to explore the possibility of a concomitant expression of weaker common tumor antigens. All the antisera reacted positively with cells of the immunizing sarcoma and these reactions were reproducible in repeated tests. In contrast, none of the antisera reacted with cells of other sarcomas. This is exemplified by tests with antiserum from rats immunized against sarcoma Mc5, which reacted with cells of this tumor but not with 10 other sarcomas. In some instances, reactions approaching that taken as positive were obtained in some tests, but these were not reproducible on reanalysis. It was found that a single test of antisarcoma Mc5 serum with sarcoma Mc31 cells gave an FI of 0.27, but a repeated test was clearly negative." @default.
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- W2488734039 date "1971-01-01" @default.
- W2488734039 modified "2023-09-28" @default.
- W2488734039 title "Tumor-Associated Antigens as Expressions of Chemically Induced Neoplasia and Their Involvement in Tumor-Host Interactions**Supported by grants from the Cancer Research Campaign and Medical Research Council." @default.
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- W2488734039 doi "https://doi.org/10.1016/b978-0-12-057550-3.50073-9" @default.
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