FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2488857548> ?p ?o ?g. }

• W2488857548 endingPage "572" @default.
• W2488857548 startingPage "566" @default.
• W2488857548 abstract "Bacterial meningitis poses diagnostic challenges in infants. Antibiotic pretreatment and low bacterial density diminish cerebrospinal fluid (CSF) culture yield, while laboratory parameters do not reliably identify bacterial meningitis. Pro and anti-inflammatory cytokines are elevated in bacterial meningitis and may be useful diagnostic adjuncts when CSF cultures are negative.In a prospective cohort study of infants, we used cytometric bead arrays to measure tumor necrosis factor alpha (TNF-α), interleukin 1 (IL-1), IL-6, IL-8, IL-10, and IL-12 in CSF. Receiver operating characteristic (ROC) analyses and Principal component analysis (PCA) were used to determine cytokine combinations that identified bacterial meningitis.Six hundred and eighty four infants < 6 mo were included; 11 had culture-proven bacterial meningitis. IL-6 and IL-10 were the individual cytokines possessing greatest accuracy in diagnosis of culture proven bacterial meningitis (ROC analyses; area under the concentration-time curve (AUC) 0.91; 0.9103 respectively), and performed as well as, or better than combinations identified using ROC and PCA. CSF cytokines were highly correlated with each other and with CSF white blood cell count (WBC) counts in infants with meningitis. A subset of antibiotic pretreated culture-negative subjects demonstrated cytokine patterns similar to culture positive subjects.CSF cytokine levels may aid diagnosis of bacterial meningitis, and facilitate decision-making regarding treatment for culture negative meningitis." @default.
• W2488857548 created "2016-08-23" @default.
• W2488857548 creator A5005942637 @default.
• W2488857548 creator A5027203858 @default.
• W2488857548 creator A5034287660 @default.
• W2488857548 creator A5045768242 @default.
• W2488857548 creator A5056393317 @default.
• W2488857548 date "2016-05-26" @default.
• W2488857548 modified "2023-10-12" @default.
• W2488857548 title "Cerebrospinal fluid cytokines in the diagnosis of bacterial meningitis in infants" @default.
• W2488857548 cites W1919528138 @default.
• W2488857548 cites W1965121358 @default.
• W2488857548 cites W2003600615 @default.
• W2488857548 cites W2019091990 @default.
• W2488857548 cites W2025017994 @default.
• W2488857548 cites W2026510962 @default.
• W2488857548 cites W2026584534 @default.
• W2488857548 cites W2039842091 @default.
• W2488857548 cites W2045819629 @default.
• W2488857548 cites W2055856136 @default.
• W2488857548 cites W2060674048 @default.
• W2488857548 cites W2064723143 @default.
• W2488857548 cites W2065290731 @default.
• W2488857548 cites W2066725378 @default.
• W2488857548 cites W2068222989 @default.
• W2488857548 cites W2081543083 @default.
• W2488857548 cites W2091637370 @default.
• W2488857548 cites W2103772309 @default.
• W2488857548 cites W2124601336 @default.
• W2488857548 cites W2133826651 @default.
• W2488857548 cites W2145254724 @default.
• W2488857548 cites W2150353529 @default.
• W2488857548 cites W2155248348 @default.
• W2488857548 cites W2169826126 @default.
• W2488857548 cites W2170431908 @default.
• W2488857548 doi "https://doi.org/10.1038/pr.2016.117" @default.
• W2488857548 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27486702" @default.
• W2488857548 hasPublicationYear "2016" @default.
• W2488857548 type Work @default.
• W2488857548 sameAs 2488857548 @default.
• W2488857548 citedByCount "32" @default.
• W2488857548 countsByYear W24888575482017 @default.
• W2488857548 countsByYear W24888575482018 @default.
• W2488857548 countsByYear W24888575482019 @default.
• W2488857548 countsByYear W24888575482020 @default.
• W2488857548 countsByYear W24888575482021 @default.
• W2488857548 countsByYear W24888575482022 @default.
• W2488857548 countsByYear W24888575482023 @default.
• W2488857548 crossrefType "journal-article" @default.
• W2488857548 hasAuthorship W2488857548A5005942637 @default.
• W2488857548 hasAuthorship W2488857548A5027203858 @default.
• W2488857548 hasAuthorship W2488857548A5034287660 @default.
• W2488857548 hasAuthorship W2488857548A5045768242 @default.
• W2488857548 hasAuthorship W2488857548A5056393317 @default.
• W2488857548 hasBestOaLocation W24888575481 @default.
• W2488857548 hasConcept C126322002 @default.
• W2488857548 hasConcept C17991360 @default.
• W2488857548 hasConcept C187212893 @default.
• W2488857548 hasConcept C189539697 @default.
• W2488857548 hasConcept C203014093 @default.
• W2488857548 hasConcept C2778488018 @default.
• W2488857548 hasConcept C2778690821 @default.
• W2488857548 hasConcept C2779651940 @default.
• W2488857548 hasConcept C2781026528 @default.
• W2488857548 hasConcept C3018430615 @default.
• W2488857548 hasConcept C501593827 @default.
• W2488857548 hasConcept C523546767 @default.
• W2488857548 hasConcept C54355233 @default.
• W2488857548 hasConcept C58471807 @default.
• W2488857548 hasConcept C71924100 @default.
• W2488857548 hasConcept C86803240 @default.
• W2488857548 hasConcept C89423630 @default.
• W2488857548 hasConceptScore W2488857548C126322002 @default.
• W2488857548 hasConceptScore W2488857548C17991360 @default.
• W2488857548 hasConceptScore W2488857548C187212893 @default.
• W2488857548 hasConceptScore W2488857548C189539697 @default.
• W2488857548 hasConceptScore W2488857548C203014093 @default.
• W2488857548 hasConceptScore W2488857548C2778488018 @default.
• W2488857548 hasConceptScore W2488857548C2778690821 @default.
• W2488857548 hasConceptScore W2488857548C2779651940 @default.
• W2488857548 hasConceptScore W2488857548C2781026528 @default.
• W2488857548 hasConceptScore W2488857548C3018430615 @default.
• W2488857548 hasConceptScore W2488857548C501593827 @default.
• W2488857548 hasConceptScore W2488857548C523546767 @default.
• W2488857548 hasConceptScore W2488857548C54355233 @default.
• W2488857548 hasConceptScore W2488857548C58471807 @default.
• W2488857548 hasConceptScore W2488857548C71924100 @default.
• W2488857548 hasConceptScore W2488857548C86803240 @default.
• W2488857548 hasConceptScore W2488857548C89423630 @default.
• W2488857548 hasIssue "4" @default.
• W2488857548 hasLocation W24888575481 @default.
• W2488857548 hasLocation W24888575482 @default.
• W2488857548 hasOpenAccess W2488857548 @default.
• W2488857548 hasPrimaryLocation W24888575481 @default.
• W2488857548 hasRelatedWork W2075617988 @default.
• W2488857548 hasRelatedWork W2107133212 @default.
• W2488857548 hasRelatedWork W2182533141 @default.
• W2488857548 hasRelatedWork W2286371939 @default.

• next