Matches in SemOpenAlex for { <https://semopenalex.org/work/W2488891822> ?p ?o ?g. }
- W2488891822 abstract "Several lines of evidence have pointed toward calcium-dependent exocytosis as a common mechanism of gliotransmitter release from astrocytes. Initial studies found increased intracellular calcium levels within astrocytes that were oscillatory and propagating. These calcium rises led to gliotransmitter release through a metabotropic glutamate receptor-dependent mechanism. Evidence for the presence of vesicular release proteins in astrocytes combined with pharmacological studies suggested an exocytosis mechanism of gliotransmitter release similar to that seen in neurons. The acceptance of this mechanism, however, became controversial after studies using transgenic mice demonstrated that increased astrocytic calcium had no effect on neighboring neurons. Astrocytic calcium signaling is altered in epilepsy. Increased intracellular calcium levels in astrocytes may lead to hyperexcitability and propagation of seizures. More in vivo studies are needed to fully understand the contribution of astrocyte calcium signaling to neuronal activity under physiological and epileptic conditions." @default.
- W2488891822 created "2016-08-23" @default.
- W2488891822 creator A5000564729 @default.
- W2488891822 creator A5012744570 @default.
- W2488891822 date "2016-01-01" @default.
- W2488891822 modified "2023-10-16" @default.
- W2488891822 title "Astrocyte Calcium Signaling" @default.
- W2488891822 cites W12316928 @default.
- W2488891822 cites W1522823711 @default.
- W2488891822 cites W1542136448 @default.
- W2488891822 cites W1547441355 @default.
- W2488891822 cites W1572171312 @default.
- W2488891822 cites W1586815960 @default.
- W2488891822 cites W1600549717 @default.
- W2488891822 cites W1629086159 @default.
- W2488891822 cites W1820680165 @default.
- W2488891822 cites W1902112862 @default.
- W2488891822 cites W1941172229 @default.
- W2488891822 cites W1943910815 @default.
- W2488891822 cites W1963711426 @default.
- W2488891822 cites W1969326379 @default.
- W2488891822 cites W1970979725 @default.
- W2488891822 cites W1972107534 @default.
- W2488891822 cites W1972988703 @default.
- W2488891822 cites W1974807815 @default.
- W2488891822 cites W1977488985 @default.
- W2488891822 cites W1980153635 @default.
- W2488891822 cites W1981134260 @default.
- W2488891822 cites W1982978441 @default.
- W2488891822 cites W1983944086 @default.
- W2488891822 cites W1990758206 @default.
- W2488891822 cites W1991807203 @default.
- W2488891822 cites W1992082068 @default.
- W2488891822 cites W1992807239 @default.
- W2488891822 cites W1993543140 @default.
- W2488891822 cites W1994357073 @default.
- W2488891822 cites W1994440562 @default.
- W2488891822 cites W1998010836 @default.
- W2488891822 cites W2000604662 @default.
- W2488891822 cites W2001628666 @default.
- W2488891822 cites W2002302413 @default.
- W2488891822 cites W2003159746 @default.
- W2488891822 cites W2006183715 @default.
- W2488891822 cites W2006395355 @default.
- W2488891822 cites W2011101653 @default.
- W2488891822 cites W201144505 @default.
- W2488891822 cites W2011531025 @default.
- W2488891822 cites W2016548054 @default.
- W2488891822 cites W2017523469 @default.
- W2488891822 cites W2025097191 @default.
- W2488891822 cites W2025513294 @default.
- W2488891822 cites W2026154459 @default.
- W2488891822 cites W2029839239 @default.
- W2488891822 cites W2030787126 @default.
- W2488891822 cites W2034086077 @default.
- W2488891822 cites W2034197019 @default.
- W2488891822 cites W2034394488 @default.
- W2488891822 cites W2038677004 @default.
- W2488891822 cites W2039067152 @default.
- W2488891822 cites W2040109036 @default.
- W2488891822 cites W2041935486 @default.
- W2488891822 cites W2045384679 @default.
- W2488891822 cites W2048105028 @default.
- W2488891822 cites W2048270592 @default.
- W2488891822 cites W2049212652 @default.
- W2488891822 cites W2049939184 @default.
- W2488891822 cites W2050452462 @default.
- W2488891822 cites W2053135501 @default.
- W2488891822 cites W2053937836 @default.
- W2488891822 cites W2054079425 @default.
- W2488891822 cites W2054153602 @default.
- W2488891822 cites W2054769944 @default.
- W2488891822 cites W2055244899 @default.
- W2488891822 cites W2062548772 @default.
- W2488891822 cites W2063796705 @default.
- W2488891822 cites W2064299691 @default.
- W2488891822 cites W2065843356 @default.
- W2488891822 cites W2070408678 @default.
- W2488891822 cites W2071971436 @default.
- W2488891822 cites W2073074276 @default.
- W2488891822 cites W2074967846 @default.
- W2488891822 cites W2076310752 @default.
- W2488891822 cites W2078102941 @default.
- W2488891822 cites W2079635232 @default.
- W2488891822 cites W2079823127 @default.
- W2488891822 cites W2080792318 @default.
- W2488891822 cites W2081173170 @default.
- W2488891822 cites W2081970214 @default.
- W2488891822 cites W2086512982 @default.
- W2488891822 cites W2087667366 @default.
- W2488891822 cites W2089736335 @default.
- W2488891822 cites W2090971379 @default.
- W2488891822 cites W2093726219 @default.
- W2488891822 cites W2093950888 @default.
- W2488891822 cites W2094026920 @default.
- W2488891822 cites W2094205031 @default.
- W2488891822 cites W2094835777 @default.
- W2488891822 cites W2095050972 @default.
- W2488891822 cites W2097254737 @default.
- W2488891822 cites W2098188545 @default.