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• W2488971541 abstract "Ying-Ying HuangWellman Center for Photomedicine, Massachusetts General Hospital, Boston MA;Department of Dermatology, Harvard Medical School, Boston MA Aesthetic Plastic Laser Center,Guangxi Medical University, Nanning, Guangxi, P. R. ChinaMichael R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Boston MA Department ofDermatology, Harvard Medical School, Boston MA Harvard-MIT Division of Health Sciences andTechnology, Cambridge MALuis De TaboadaPhotoThera Inc, Carlsbad, CA27.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71827.2 Photobiology of Low-Level Laser Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71827.3 LLLT Effects on Nerves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71927.4 Human Skull Transmission Measurements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72027.5 The Problem of Stroke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72127.6 TLT for Stroke . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72427.7 LLLT for CNS Damage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72727.8 LLLT for Neurodegenerative Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73027.9 LLLT for Psychiatric Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73127.10Conclusions and Future Outlook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 731References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 733Low-level laser/light therapy (LLLT) for neurological disorders in the central nervous system (CNS)is currently an experimental concept. The broad goals for clinical utilization are the preventionand/or repair of damage, relief of symptoms, slowing of disease progression, and correction of genetic abnormalities. Experimental studies have tested and continue to test these goals by investigating LLLT in animal models of diseases and injuries that affect the brain and spinal cord. Successfulclinical trials have been carried out of transcranial laser therapy for stroke. Discoveries concerningthe molecular basis of various neurological diseases, combined with advances that have been madein understanding the molecular and cellular mechanisms in LLLT, both in vitro and in vivo, haveallowed rational light-based therapeutic approaches for a wide variety of CNS disorders to be investigated. Limitations in knowledge are still apparent, such as the optimal wavelength, light source,doses, pulsed or CW, polarization state, treatment timing, and repetition frequency. Collaborativeefforts between clinicians and basic researchers will likely increase the usage and understanding ofeffective laser-based therapies in the CNS." @default.
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• W2488971541 date "2010-05-18" @default.
• W2488971541 modified "2023-09-24" @default.
• W2488971541 title "Low-Level Laser Therapy in Stroke and Central Nervous System" @default.
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• W2488971541 doi "https://doi.org/10.1201/9781439806296-c27" @default.
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