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- W2488992876 abstract "Exocytotic fusion of secretory vesicles with the plasma membrane occurs in cells in either a constitutive or regulated fashion (Burgess and Kelly, 1987). Constitutive exocytosis is the mechanism by which membrane components and certain soluble proteins are released. In the regulated secretory pathway, secretory products are stored in secretory vesicles until exocytois is triggered by an intracellular signal, and is the pathway for secretion of neurotransmitters and many hormones. The regulated secretory pathways in neurons and secretory cells have a number of aspects in common (Cheek and Burgoyne, 1990), and we and many others have chosen to study the bovine adrenal chromaffin cell as a convenient model system for the investigation of regulated exocytosis (Burgoyne, 1984a; Kink and Knight, 1988; Winkler, 1988). This chapter will concentrate on work on adrenal chromaffin cells (Fig. 1) with some reference to exocytosis in other secretory cells, and will cover experimental approaches that have been used in the study of the intracellular regulators and mediators of exocytosis in chromaffin cells. Open image in new window Fig. 1. General scheme showing the control of exocytosis in bovine adrenal chromaffin cells. The sources of Ca2+ include entry from outside and release from two separate internal stores. The cytoskeletal barrier at the cell cortex is disassembled in response to Ca2+ or activation of protein kinase C. The exocytotic machinery is shown as a shaded box. Following exocytosis, vesicle membrane is recovered by endocytosis through coated vesicles. Abbreviations: pIc, phosphoinositidase C; pKc, protein kinase C ACh, acetylcholine; m, muscarinic receptor; n, nicotinic receptor." @default.
- W2488992876 created "2016-08-23" @default.
- W2488992876 creator A5005167203 @default.
- W2488992876 date "2003-11-14" @default.
- W2488992876 modified "2023-09-25" @default.
- W2488992876 title "Investigation of the Intracellular Regulators and Components of the Exocytotic Pathway" @default.
- W2488992876 cites W1482513578 @default.
- W2488992876 cites W1489232619 @default.
- W2488992876 cites W1507967068 @default.
- W2488992876 cites W1523098832 @default.
- W2488992876 cites W1539275723 @default.
- W2488992876 cites W1557259285 @default.
- W2488992876 cites W1561146956 @default.
- W2488992876 cites W1585941552 @default.
- W2488992876 cites W1588129438 @default.
- W2488992876 cites W1613128607 @default.
- W2488992876 cites W1619033851 @default.
- W2488992876 cites W1656215571 @default.
- W2488992876 cites W1803227917 @default.
- W2488992876 cites W1966138684 @default.
- W2488992876 cites W1966379399 @default.
- W2488992876 cites W1970249565 @default.
- W2488992876 cites W1970447122 @default.
- W2488992876 cites W1971936465 @default.
- W2488992876 cites W1973417166 @default.
- W2488992876 cites W1975653396 @default.
- W2488992876 cites W1976596241 @default.
- W2488992876 cites W1977785728 @default.
- W2488992876 cites W1981746120 @default.
- W2488992876 cites W1984540625 @default.
- W2488992876 cites W1986935245 @default.
- W2488992876 cites W1987411433 @default.
- W2488992876 cites W1987482586 @default.
- W2488992876 cites W1993062495 @default.
- W2488992876 cites W1997458769 @default.
- W2488992876 cites W2001189695 @default.
- W2488992876 cites W2003292274 @default.
- W2488992876 cites W2003498227 @default.
- W2488992876 cites W2004028505 @default.
- W2488992876 cites W2004533638 @default.
- W2488992876 cites W2005886367 @default.
- W2488992876 cites W2007169332 @default.
- W2488992876 cites W2007514577 @default.
- W2488992876 cites W2010409183 @default.
- W2488992876 cites W2010804128 @default.
- W2488992876 cites W2011292527 @default.
- W2488992876 cites W2013026243 @default.
- W2488992876 cites W2015716763 @default.
- W2488992876 cites W2020592367 @default.
- W2488992876 cites W2023730412 @default.
- W2488992876 cites W2024988208 @default.
- W2488992876 cites W2024994073 @default.
- W2488992876 cites W2026200473 @default.
- W2488992876 cites W2026375108 @default.
- W2488992876 cites W2031478867 @default.
- W2488992876 cites W2036320945 @default.
- W2488992876 cites W2036590430 @default.
- W2488992876 cites W2036632111 @default.
- W2488992876 cites W2038544226 @default.
- W2488992876 cites W2044747597 @default.
- W2488992876 cites W2046073363 @default.
- W2488992876 cites W2049685276 @default.
- W2488992876 cites W2050917391 @default.
- W2488992876 cites W2054824306 @default.
- W2488992876 cites W2057163724 @default.
- W2488992876 cites W2057804938 @default.
- W2488992876 cites W2058310224 @default.
- W2488992876 cites W2059224296 @default.
- W2488992876 cites W2060120512 @default.
- W2488992876 cites W2064473372 @default.
- W2488992876 cites W2064803671 @default.
- W2488992876 cites W2065955199 @default.
- W2488992876 cites W2068921858 @default.
- W2488992876 cites W2069448376 @default.
- W2488992876 cites W2071798630 @default.
- W2488992876 cites W2073400297 @default.
- W2488992876 cites W2073521953 @default.
- W2488992876 cites W2074321236 @default.
- W2488992876 cites W2075132080 @default.
- W2488992876 cites W2076539707 @default.
- W2488992876 cites W2077538811 @default.
- W2488992876 cites W2081321223 @default.
- W2488992876 cites W2085965046 @default.
- W2488992876 cites W2090589095 @default.
- W2488992876 cites W2091432500 @default.
- W2488992876 cites W2092991823 @default.
- W2488992876 cites W2094005271 @default.
- W2488992876 cites W2102686118 @default.
- W2488992876 cites W2106463709 @default.
- W2488992876 cites W2106978100 @default.
- W2488992876 cites W2109440146 @default.
- W2488992876 cites W2118459609 @default.
- W2488992876 cites W2123065833 @default.
- W2488992876 cites W2128440593 @default.
- W2488992876 cites W2132519244 @default.
- W2488992876 cites W2137940168 @default.
- W2488992876 cites W2140116624 @default.
- W2488992876 cites W2140763168 @default.