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• W2489803574 abstract "Abstract: Internal organ motions are one of the most significant obstacles for radiotherapy, especially in the case of motions caused by respiratory during the lung irradiation. There is no any consensus about the margin limit given for the target volume (Clinical Target Volume-CTV, Planning Target Volume- PTV etc.), especially for tumors located moving organs such as lung. Besides, as far as we know, there is no any systematic phantom study showed the effects of respiratory motions on radiotherapy doses depending on PTV margins in the literature. In present study, our aim was to determine the success degree of enlarging the PTV margins on radiotherapy doses during the moving organ irradiations. The study was performed by using GaF-Chromic EBT films placed to a thorax phantom. A cylindrical part within the phantom can move on through craniocaudal direction with a range of 3 cm with 5 sec. period during the irradiation. From the profiles which were obtained from 3 cm moving situations for 3D-Conformal Radiotherapy (3D-CRT), Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) with narrow margins, it was observed that PTV cannot get adequate dose. The irradiation was better for CTV with larger margins but there was still inhomogeneity for PTV. As a consequence, enlarging the margins alone is not a sufficient method against the negative effects of organ motions on the radiotherapy doses. Key words: Radiotherapy, lung movement, respiratory Akciger Kanseri Radyoterapisinde Solunumun Doz Dagilimlarina Etkisi: Bir Fantom Calismasi Ozet: Organ hareketleri, ozellikle akciger isinlamalari sirasinda nefes alip vermeden kaynaklanan hareketler, radyoterapi icin en onemli zorluklardandir. Ozellikle akciger gibi hareketli organlarda bulunan tumorler icin hedef hacme (Clinical Target Volume-CTV, Planning Target Volume- PTV) verilecek marj siniri hakkinda herhangi bir fikir birligi yoktur. Bunun yaninda, literaturde solunum hareketlerinin PTV marjlarina bagli olarak radyoterapi dozlarina etkisini gosteren sistematik bir fontom calismasi bulunmamaktadir. Bu calismada amac, PTV marjlarinin genislemesinin, organ hareketlerinin radyoterapi dozlarina etkileri uzerindeki basarisini olcmektir. Calisma GaF-Chromic EBT filmlerin bir gogus kafesi fantomuna yerlestirilmesiyle gerceklestirilmistir. Fantom icerisindeki bir silindirik bolum isinlama sirasinda 5 saniyelik periyotlarla, 3 cm genlikle ayak-bas dogrultusunda hareket etmektedir. 3 cm genlikli hareketin oldugu durum icin alinan profillerden 3 Boyutlu Konformal Radyoterapi (3D-CRT), Yogunluk Ayarli Radyoterapi (IMRT), Yogunluk Ayarli Arc Tedavi (VMAT) planlari dar marjlar icin incelendiginde, PTV’nin yeterli doz alamadigi gozlemlenmistir. Isinlama CTV icin daha genis marjlarda iyilesmekte, ancak PTV icin inhomojenite devam etmektedir. Sonuc olarak, marjlarin genisletilmesinin organ hareketlerinin radyoterapi dozlari uzerindeki olumsuz etkileri icin tek basina yeterli olmadigi gozlemlenmistir. Anahtar kelimeler: Radyoterapi, akciger hareketi, solunum" @default.
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• W2489803574 date "2016-05-24" @default.
• W2489803574 modified "2023-09-28" @default.
• W2489803574 title "The Effect of Respiratory on Dose Distributions in Radiotherapy of Lung Cancer: A Phantom Study" @default.
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