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• W2490156230 abstract "Objective: While Obstructive sleep apnea (OSA) is associated with increased risk of arterial hypertension and adverse cardiovascular outcomes, the link between arterial hypertension and periodic limb movement during sleep (PLMS), with or without OSA, is still controversial. Design and method: A cross-sectional analysis of 2686 participants in the multinational European Sleep Apnoea Cohort (ESADA) study was performed, by assessing the relation of blood pressure (BP) values (systolic and diastolic) with PLMS in subjects with or without OSA. All patients underwent full polysomnography (PSG) and office BP evaluation. From the polysomnographic examination we obtained quantification of OSA by assessing the apnea-hypopnea index (AHI) and quantification of PLMS as quantified by PLMS index (PLMSI). Results: 1528 subjects (1036 males, mean age 51 yrs, mean BMI 30) were included in the final cohort. To analyze the relationship between office blood pressure values (systolic and diastolic), and AHI and PLMSI we identified four patients’ groups according to the AHI and PLMSI results as following: Group 1 (N = 120) patients with PLMSI > = 25 and AHI > = 10; Group 2 (N = 992) PLMSI < 25 and AHI > = 10; Group 3 (N = 21) PLMSI > = 25 and AHI < 10; Group 4 (N = 395) PLMSI <25 and AHI<10. Systolic and diastolic blood pressure means estimated by ANCOVA models for each group are shown in Table 1. The p-values are related to the contrasts between each group mean and reference group mean (Group 1).The mean of systolic blood pressure was significantly higher in group 1 as compared with group 4. No significant differences we observed in diastolic values. Conclusions: Our results confirm the link between apnea-hypopnea index and BP levels. The novel observation of our study is that the simultaneous presence of OSA and PLMS is associated with significantly higher office BP values than in OSA patients without PLMS. Further studies are needed to better characterize such an association by assessing the link between PLMS and 24 h ambulatory BP." @default.
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• W2490156230 date "2016-09-01" @default.
• W2490156230 modified "2023-10-18" @default.
• W2490156230 title "[OP.8B.01] PERIODIC LIMB MOVEMENT DURING SLEEP, SLEEP RELATED BREATHING DISORDERS AND HYPERTENSION IN THE ESADA COHORT" @default.
• W2490156230 doi "https://doi.org/10.1097/01.hjh.0000491592.23399.e4" @default.
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