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- W2490863734 abstract "Gas flow in the airway and lung deformation due to tissue elasticity and surface tension are the main characteristics of respiratory dynamics. In this study, the simulation with the discretized model as a distributed parameter system is used extensively to identify some of the model parameters which could not be measured directly and to estimate the real situation of the lung respiration. By using 5 excised lungs from Japanese white rabbits, the pleural pressure vs. lung volume change (Ppt-ΔV)relations are observed in situ under oscillating pleural pressure. The elastic properties of the lung tissue are measured under biaxial tension. The unknown parameters, such as that for the surface tension in the alveoli, are identified so that the calculated Ppt-ΔV relations based on simulation coincide with the experimental results for each lung. The simulation studies with the identified parameter demonstrate the potential to estimate the real phenomena inside the excised lung." @default.
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- W2490863734 date "1991-01-01" @default.
- W2490863734 modified "2023-09-26" @default.
- W2490863734 title "Parameter Identification for Respiratory Dynamics by Personalized Simulation and Experiment." @default.
- W2490863734 doi "https://doi.org/10.1299/kikaia.57.1252" @default.
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