FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2492321478> ?p ?o ?g. }

• W2492321478 endingPage "74" @default.
• W2492321478 startingPage "65" @default.
• W2492321478 abstract "Most cost-effectiveness analyses of hepatitis C (HCV) therapy focus on the benefits of reducing liver-related morbidity and mortality.Our objective was to assess how cost-effectiveness estimates of HCV therapy can vary depending on assumptions regarding the potential impact of HCV therapy on non-hepatic mortality.We adapted a state-transition model to include potential effects of HCV therapy on non-hepatic mortality. We assumed successful treatment could reduce non-hepatic mortality by as little as 0 % to as much as 100 %. Incremental cost-effectiveness ratios were computed comparing immediate treatment versus delayed treatment and comparing immediate treatment versus non-treatment.Comparing immediate treatment versus delayed treatment, when we included a 44 % reduction in non-hepatic mortality following successful HCV treatment, the incremental cost per quality-adjusted life year (QALY) gained by HCV treatment fell by 76 % (from US$314,100 to US$76,900) for patients with no fibrosis and by 43 % (from US$62,500 to US$35,800) for patients with moderate fibrosis. Comparing immediate treatment versus non-treatment, assuming a 44 % reduction in non-hepatic mortality following successful HCV treatment, the incremental cost per QALY gained by HCV treatment fell by 64 % (from US$186,700 to US$67,300) for patients with no fibrosis and by 27 % (from US$35,000 to US$25,500) for patients with moderate fibrosis.Including reductions in non-hepatic mortality from HCV treatment can have substantial effects on the estimated cost-effectiveness of treatment." @default.
• W2492321478 created "2016-08-23" @default.
• W2492321478 creator A5020714737 @default.
• W2492321478 creator A5049251557 @default.
• W2492321478 creator A5051066960 @default.
• W2492321478 creator A5081055053 @default.
• W2492321478 date "2016-08-01" @default.
• W2492321478 modified "2023-10-12" @default.
• W2492321478 title "Assessing the Effect of Potential Reductions in Non-Hepatic Mortality on the Estimated Cost-Effectiveness of Hepatitis C Treatment in Early Stages of Liver Disease" @default.
• W2492321478 cites W1502488305 @default.
• W2492321478 cites W1588369580 @default.
• W2492321478 cites W162603234 @default.
• W2492321478 cites W1717835252 @default.
• W2492321478 cites W1717970182 @default.
• W2492321478 cites W1753385857 @default.
• W2492321478 cites W1847544154 @default.
• W2492321478 cites W1857591791 @default.
• W2492321478 cites W1893031753 @default.
• W2492321478 cites W1910533708 @default.
• W2492321478 cites W1915531325 @default.
• W2492321478 cites W1934982766 @default.
• W2492321478 cites W1944458049 @default.
• W2492321478 cites W1979020141 @default.
• W2492321478 cites W1980154502 @default.
• W2492321478 cites W1983488380 @default.
• W2492321478 cites W1991395575 @default.
• W2492321478 cites W1993189159 @default.
• W2492321478 cites W1994850182 @default.
• W2492321478 cites W2004302285 @default.
• W2492321478 cites W2004461455 @default.
• W2492321478 cites W2007151849 @default.
• W2492321478 cites W2008646009 @default.
• W2492321478 cites W2011880652 @default.
• W2492321478 cites W2015172755 @default.
• W2492321478 cites W2021508522 @default.
• W2492321478 cites W2022967348 @default.
• W2492321478 cites W2026933790 @default.
• W2492321478 cites W2036181602 @default.
• W2492321478 cites W2039764712 @default.
• W2492321478 cites W2044349000 @default.
• W2492321478 cites W2045245188 @default.
• W2492321478 cites W2048075325 @default.
• W2492321478 cites W2052270403 @default.
• W2492321478 cites W2052313548 @default.
• W2492321478 cites W2054882786 @default.
• W2492321478 cites W2058366033 @default.
• W2492321478 cites W2060528034 @default.
• W2492321478 cites W2063029514 @default.
• W2492321478 cites W2067281613 @default.
• W2492321478 cites W2075642745 @default.
• W2492321478 cites W2077958167 @default.
• W2492321478 cites W2078799829 @default.
• W2492321478 cites W2079278825 @default.
• W2492321478 cites W2080420644 @default.
• W2492321478 cites W2082066550 @default.
• W2492321478 cites W2082508303 @default.
• W2492321478 cites W2084475148 @default.
• W2492321478 cites W2085866934 @default.
• W2492321478 cites W2086307899 @default.
• W2492321478 cites W2088095316 @default.
• W2492321478 cites W2091242637 @default.
• W2492321478 cites W2092015313 @default.
• W2492321478 cites W2098535521 @default.
• W2492321478 cites W2106485849 @default.
• W2492321478 cites W2107312551 @default.
• W2492321478 cites W2117129614 @default.
• W2492321478 cites W2117490789 @default.
• W2492321478 cites W2117700123 @default.
• W2492321478 cites W2118771356 @default.
• W2492321478 cites W2120839943 @default.
• W2492321478 cites W2121062250 @default.
• W2492321478 cites W2122633715 @default.
• W2492321478 cites W2124332805 @default.
• W2492321478 cites W2125586696 @default.
• W2492321478 cites W2132726958 @default.
• W2492321478 cites W2133080576 @default.
• W2492321478 cites W2148341406 @default.
• W2492321478 cites W2152870084 @default.
• W2492321478 cites W2153535100 @default.
• W2492321478 cites W2153720399 @default.
• W2492321478 cites W2162317388 @default.
• W2492321478 cites W2164668044 @default.
• W2492321478 cites W2167447251 @default.
• W2492321478 cites W2171147538 @default.
• W2492321478 cites W2171540368 @default.
• W2492321478 cites W2178511310 @default.
• W2492321478 cites W2179707291 @default.
• W2492321478 cites W2210591412 @default.
• W2492321478 cites W2229638189 @default.
• W2492321478 cites W2288320856 @default.
• W2492321478 cites W2292517844 @default.
• W2492321478 cites W2345055725 @default.
• W2492321478 cites W2345197548 @default.
• W2492321478 cites W2413814927 @default.
• W2492321478 cites W3001324056 @default.
• W2492321478 cites W4237167198 @default.
• W2492321478 cites W4254347167 @default.
• W2492321478 cites W2137750987 @default.

• next