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- W2492651027 abstract "SUMMARY The efficacy of horizontal and vertical laminar flow units (equipped with highefficiency air filters) in the prevention of cross-contamination between cages and of contamination from outside has been demonstrated. With germ-free mice and using germ-free standard techniques for sterilization and for the transfer of germfree mice into the cabinets via. a standard entry lock, it was found that during an observabion period of 2 weeks the animaUls rema.in 'negative'. Other experiments were performed with equally good results in cabinets equipped with a hinged flap, closing 95 °/O of the open front side. When the flap was closed bhe air flow could be reduced accordingly, thus reducing the noise level and the risk of dehydration. Experiments made with germ-free mice in a 'down-flow unit' were aJlso invariably good. In another type of experiment, cages with conventional mice were placed in the cabinets between cages with germ-free animals a,t va.rying distances. If a11 anima,ls were maintained on wire mesh (to minimize the aerosol produebion of dust) and if the ' conventional ' cages were a,t a distance of 10 cm. from 'germ-free cages ' the latter remained bacteria-free during test periods of one week. The use of 'laminar flow isolators' for the isolation of human patients is mentioned." @default.
- W2492651027 created "2016-08-23" @default.
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- W2492651027 date "2016-01-01" @default.
- W2492651027 modified "2023-09-27" @default.
- W2492651027 title "Prevention of airborne contamination and cross-contamination in germ-free mice by laminar flow BY D. VAN DER WAAIJ AND A. H. ANDREAS" @default.
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- W2492651027 hasPublicationYear "2016" @default.
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