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- W2493632145 endingPage "183" @default.
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- W2493632145 abstract "Abstract Research ethics has focused on protecting the autonomy of the individual research subject, insisting on informed consent and a reasonable risk/benefit ratio for a study to be ethical. At the same time, it has largely ignored the situation of the “indirect participant” in research: someone who might be adversely affected by another's participation in a research study. There are many historical examples of this failure: self-experimentation with infectious disease, the Tuskegee syphilis study, and the Willowbrook study of infectious hepatitis, among others. And there are many more contemporary examples, too, such as tests of the oral polio vaccine or of short-course anti-retroviral therapy for HIV+ pregnant women. This chapter argues that risks to indirect participants must be considered in assessing the risk/benefit ratio of study designs. Where there are identifiable indirect participants and risks to them are significant, their informed consent should also be required for participation of the direct subject in research. Where indirect participants cannot easily be identified, but risks may be substantial, the chapter suggest employing models drawn from community consent to conduct of research." @default.
- W2493632145 created "2016-08-23" @default.
- W2493632145 creator A5003407284 @default.
- W2493632145 creator A5011069226 @default.
- W2493632145 creator A5036765917 @default.
- W2493632145 creator A5076599658 @default.
- W2493632145 date "2009-01-08" @default.
- W2493632145 modified "2023-09-26" @default.
- W2493632145 title "The Ethics of Research in Infectious Disease:" @default.
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