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- W2493744488 abstract "Fluroolefin dipeptide isosteres were synthesized applying the Peterson reaction as a novel method for fluoroolefination. Gly-ψ[CF=C]-Pro dipeptide isosteres were elaborated to provide conformationally constrained analogs of the Suc-Ala-Gly-Pro-Phe-pNA tetrapeptide substrate for cyclophilin. Ala-ψ[CF=C]-Pro containing N,O-diacylhydroxamic acid type protease inhibitors were synthesized for the study of the influence of prolylamide bond geometry on the inhibition of dipeptidyl peptidase IV(CD26)." @default.
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- W2493744488 date "1996-08-13" @default.
- W2493744488 modified "2023-09-25" @default.
- W2493744488 title "Fluoro-olefin Isosteres as Peptidomimetics" @default.
- W2493744488 doi "https://doi.org/10.1021/bk-1996-0639.ch010" @default.
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