FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2494572510> ?p ?o ?g. }

• W2494572510 endingPage "219" @default.
• W2494572510 startingPage "203" @default.
• W2494572510 abstract "It is perhaps not surprising that an inhospitable intrauterine environment can result in neurodevelopmental disorders, given the enormous changes in brain development that occur during gestation. Here we discuss: (1) Obesity is a state of low-grade inflammation and is thus a candidate for having an unfavorable impact on brain function in the offspring. (2) Maternal obesity has recently been associated with offspring attention deficit hyperactivity disorder and autism spectrum disorder. A recent study found differences in amniotic fluid mRNA for 20 genes in fetuses of obese versus lean women, and several of these genes impact on brain sculpting. (3) The balance between excitable and inhibitory neural function can be disturbed as a consequence of maternal obesity and can lead to hyperexcitability-linked cognitive decline later in life. (4) While most studies of brain development and function have focused on neurons, inflammation and oxidative stress have major effects on microglia and astrocytes, key cells in the sculpting of synapses, neural plasticity, and the formation of neural networks. (5) Animal models are, of necessity, widely used and the temporal trajectory of neurodevelopment to accommodate the requirements of the different species has recently been modeled. While detailed studies are essential for understanding mechanism, it is critical to test the outcomes of manipulating the system on behavior. In this regard considerable care is required to ensure that the most appropriate behavioral test and animal model are used. Thus, there is considerable scope for consolidating our understanding of the effects of maternal obesity on brain function in the offspring." @default.
• W2494572510 created "2016-08-23" @default.
• W2494572510 creator A5006764099 @default.
• W2494572510 creator A5029409684 @default.
• W2494572510 date "2016-01-01" @default.
• W2494572510 modified "2023-09-25" @default.
• W2494572510 title "Maternal Obesity in Pregnancy: Consequences for Brain Function in the Offspring" @default.
• W2494572510 cites W114074157 @default.
• W2494572510 cites W1525738413 @default.
• W2494572510 cites W1564190433 @default.
• W2494572510 cites W1569284316 @default.
• W2494572510 cites W1623365227 @default.
• W2494572510 cites W1838573128 @default.
• W2494572510 cites W1866620858 @default.
• W2494572510 cites W1937405158 @default.
• W2494572510 cites W1967417871 @default.
• W2494572510 cites W1968362444 @default.
• W2494572510 cites W1968636032 @default.
• W2494572510 cites W1970910654 @default.
• W2494572510 cites W1972275518 @default.
• W2494572510 cites W1973441265 @default.
• W2494572510 cites W1974696451 @default.
• W2494572510 cites W1975146958 @default.
• W2494572510 cites W1976010325 @default.
• W2494572510 cites W1979612107 @default.
• W2494572510 cites W1980458830 @default.
• W2494572510 cites W1981003144 @default.
• W2494572510 cites W1981446305 @default.
• W2494572510 cites W1983100194 @default.
• W2494572510 cites W1984248473 @default.
• W2494572510 cites W1984907756 @default.
• W2494572510 cites W1985819825 @default.
• W2494572510 cites W1987709429 @default.
• W2494572510 cites W1990413385 @default.
• W2494572510 cites W1997396304 @default.
• W2494572510 cites W2000219660 @default.
• W2494572510 cites W2001056499 @default.
• W2494572510 cites W2003969692 @default.
• W2494572510 cites W2004349171 @default.
• W2494572510 cites W2005016731 @default.
• W2494572510 cites W2010363777 @default.
• W2494572510 cites W2011900900 @default.
• W2494572510 cites W2012150468 @default.
• W2494572510 cites W2016818296 @default.
• W2494572510 cites W2020429579 @default.
• W2494572510 cites W2022567100 @default.
• W2494572510 cites W2023044037 @default.
• W2494572510 cites W2023295081 @default.
• W2494572510 cites W2023556968 @default.
• W2494572510 cites W2024021877 @default.
• W2494572510 cites W2026802237 @default.
• W2494572510 cites W2028861833 @default.
• W2494572510 cites W2030279915 @default.
• W2494572510 cites W2031492796 @default.
• W2494572510 cites W2031766661 @default.
• W2494572510 cites W2033114609 @default.
• W2494572510 cites W2034591666 @default.
• W2494572510 cites W2037175431 @default.
• W2494572510 cites W2040991888 @default.
• W2494572510 cites W2042959171 @default.
• W2494572510 cites W2047104170 @default.
• W2494572510 cites W2048246446 @default.
• W2494572510 cites W2050705896 @default.
• W2494572510 cites W2050744136 @default.
• W2494572510 cites W2051215863 @default.
• W2494572510 cites W2056045580 @default.
• W2494572510 cites W2056425307 @default.
• W2494572510 cites W2062513530 @default.
• W2494572510 cites W2062999146 @default.
• W2494572510 cites W2063324016 @default.
• W2494572510 cites W2064489601 @default.
• W2494572510 cites W2065536873 @default.
• W2494572510 cites W2068094413 @default.
• W2494572510 cites W2068687319 @default.
• W2494572510 cites W2070381267 @default.
• W2494572510 cites W2071103930 @default.
• W2494572510 cites W2080131125 @default.
• W2494572510 cites W2082087977 @default.
• W2494572510 cites W2085202176 @default.
• W2494572510 cites W2096500024 @default.
• W2494572510 cites W2096961422 @default.
• W2494572510 cites W2100216755 @default.
• W2494572510 cites W2105673253 @default.
• W2494572510 cites W2106137569 @default.
• W2494572510 cites W2107764762 @default.
• W2494572510 cites W2113584025 @default.
• W2494572510 cites W2117579257 @default.
• W2494572510 cites W2117837208 @default.
• W2494572510 cites W2127491389 @default.
• W2494572510 cites W2127619125 @default.
• W2494572510 cites W2127922953 @default.
• W2494572510 cites W2130525167 @default.
• W2494572510 cites W2135591161 @default.
• W2494572510 cites W2142654785 @default.
• W2494572510 cites W2143584397 @default.
• W2494572510 cites W2145425898 @default.
• W2494572510 cites W2145683389 @default.
• W2494572510 cites W2146678583 @default.

• next