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- W249486536 endingPage "12" @default.
- W249486536 startingPage "1" @default.
- W249486536 abstract "Helicases are essential enzymes involved in all aspects of nucleic acid metabolism including DNA replication, repair, recombination, transcription, ribosome biogenesis and RNA processing, translation, and decay. They occur in vivo as part of molecular complexes that include the components required for each specific step of nucleic acid metabolism. The role of the helicases is to utilize the energy derived from nucleoside triphosphate hydrolysis to translocate along nucleic acid strands, unwind/separate the helical structure of double-stranded nucleic acid, and, in some cases, disrupt protein–nucleic acid interactions. Because of their essential function, helicases are ubiquitous and evolutionary conserved proteins. This chapter briefly highlights helicase structure and activities and provides examples of the helicases involved in nucleic acid metabolism." @default.
- W249486536 created "2016-06-24" @default.
- W249486536 creator A5069537382 @default.
- W249486536 date "2009-01-01" @default.
- W249486536 modified "2023-10-06" @default.
- W249486536 title "Helicases: An Overview" @default.
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