FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2495109752> ?p ?o ?g. }

• W2495109752 endingPage "139" @default.
• W2495109752 startingPage "123" @default.
• W2495109752 abstract "Tritiated thymidineTritiated thymidine ([3H]dT[H]dT ) and its analogs bromodeoxyuridinebromodeoxyuridine (BrdUBrdU ), iododeoxyuridineiododeoxyuridine (IdUIdU ), chlorodeoxyuridinechlorodeoxyuridine (CldUCldU ), and ethynyl deoxyuridineethynyl deoxyuridine (EdUEdU ) are used extensively to study neuronalneuronal time of originorigin and pattern of migrationmigration . Here, we discuss the advantages and pitfalls of identifying dividing cellsdividing cells with these markersmarkers and emphasize that they simply indicate DNADNA synthesisDNA synthesis . Thus, in addition to dividing cells, they can label cells that are undergoing DNA repairDNA repair and/or cell deathcell death . As foreign molecules in the DNA, these markers can affect the kineticskinetics of cell proliferationcell proliferation and also have unpredictable functional consequences. We review general protocols and present evidence, based on our own studies in nonhumannon-human primatesprimates , that cell proliferationproliferation , as indicated by cell numberscell numbers and/or their survivalsurvival , as well as the localization of migrating cells, may be affected by the labelinglabeling method itself. We show that measurements made using [3H]dT labeling are more accurate than those using BrdU, perhaps because [3H]dT is less toxictoxic . Thus, utmost caution should be exercised when interpreting the results obtained by using thymidinethymidine analogsthymidine analogs as possible indicators of the number of mitotic divisionsmitotic divisions , patterns of migration, final positionspositions , and ultimate fatefate of cells." @default.
• W2495109752 created "2016-08-23" @default.
• W2495109752 creator A5038455977 @default.
• W2495109752 creator A5089868470 @default.
• W2495109752 date "2015-01-01" @default.
• W2495109752 modified "2023-09-26" @default.
• W2495109752 title "Identification of Proliferating and Migrating Cells by BrdU and Other Thymidine Analogs: Benefits and Limitations" @default.
• W2495109752 cites W1000015476 @default.
• W2495109752 cites W1513166852 @default.
• W2495109752 cites W1589449569 @default.
• W2495109752 cites W1926043920 @default.
• W2495109752 cites W1935951477 @default.
• W2495109752 cites W1967946279 @default.
• W2495109752 cites W1968652549 @default.
• W2495109752 cites W1975639021 @default.
• W2495109752 cites W1976617687 @default.
• W2495109752 cites W1979952856 @default.
• W2495109752 cites W1983851782 @default.
• W2495109752 cites W1984996991 @default.
• W2495109752 cites W2003935374 @default.
• W2495109752 cites W2004204081 @default.
• W2495109752 cites W2005354143 @default.
• W2495109752 cites W2007060410 @default.
• W2495109752 cites W2013466759 @default.
• W2495109752 cites W2022491750 @default.
• W2495109752 cites W2031468048 @default.
• W2495109752 cites W2042718792 @default.
• W2495109752 cites W2045295673 @default.
• W2495109752 cites W2072673889 @default.
• W2495109752 cites W2076432328 @default.
• W2495109752 cites W2077110494 @default.
• W2495109752 cites W2078626145 @default.
• W2495109752 cites W2079659108 @default.
• W2495109752 cites W2094073595 @default.
• W2495109752 cites W2094502567 @default.
• W2495109752 cites W2103272211 @default.
• W2495109752 cites W2117389252 @default.
• W2495109752 cites W2119471783 @default.
• W2495109752 cites W2123239051 @default.
• W2495109752 cites W2131468115 @default.
• W2495109752 cites W2139123731 @default.
• W2495109752 cites W2139481908 @default.
• W2495109752 cites W2159262521 @default.
• W2495109752 cites W2169557197 @default.
• W2495109752 cites W2497546886 @default.
• W2495109752 cites W2791952348 @default.
• W2495109752 cites W4211031782 @default.
• W2495109752 cites W4248522153 @default.
• W2495109752 doi "https://doi.org/10.1007/978-1-4939-2313-7_7" @default.
• W2495109752 hasPublicationYear "2015" @default.
• W2495109752 type Work @default.
• W2495109752 sameAs 2495109752 @default.
• W2495109752 citedByCount "5" @default.
• W2495109752 countsByYear W24951097522018 @default.
• W2495109752 countsByYear W24951097522019 @default.
• W2495109752 countsByYear W24951097522020 @default.
• W2495109752 countsByYear W24951097522021 @default.
• W2495109752 crossrefType "book-chapter" @default.
• W2495109752 hasAuthorship W2495109752A5038455977 @default.
• W2495109752 hasAuthorship W2495109752A5089868470 @default.
• W2495109752 hasConcept C1491633281 @default.
• W2495109752 hasConcept C153911025 @default.
• W2495109752 hasConcept C185592680 @default.
• W2495109752 hasConcept C2777108182 @default.
• W2495109752 hasConcept C2777111502 @default.
• W2495109752 hasConcept C2778260397 @default.
• W2495109752 hasConcept C54355233 @default.
• W2495109752 hasConcept C552990157 @default.
• W2495109752 hasConcept C62112901 @default.
• W2495109752 hasConcept C64241487 @default.
• W2495109752 hasConcept C70721500 @default.
• W2495109752 hasConcept C86803240 @default.
• W2495109752 hasConcept C93304396 @default.
• W2495109752 hasConcept C95444343 @default.
• W2495109752 hasConceptScore W2495109752C1491633281 @default.
• W2495109752 hasConceptScore W2495109752C153911025 @default.
• W2495109752 hasConceptScore W2495109752C185592680 @default.
• W2495109752 hasConceptScore W2495109752C2777108182 @default.
• W2495109752 hasConceptScore W2495109752C2777111502 @default.
• W2495109752 hasConceptScore W2495109752C2778260397 @default.
• W2495109752 hasConceptScore W2495109752C54355233 @default.
• W2495109752 hasConceptScore W2495109752C552990157 @default.
• W2495109752 hasConceptScore W2495109752C62112901 @default.
• W2495109752 hasConceptScore W2495109752C64241487 @default.
• W2495109752 hasConceptScore W2495109752C70721500 @default.
• W2495109752 hasConceptScore W2495109752C86803240 @default.
• W2495109752 hasConceptScore W2495109752C93304396 @default.
• W2495109752 hasConceptScore W2495109752C95444343 @default.
• W2495109752 hasLocation W24951097521 @default.
• W2495109752 hasOpenAccess W2495109752 @default.
• W2495109752 hasPrimaryLocation W24951097521 @default.
• W2495109752 hasRelatedWork W2000987057 @default.
• W2495109752 hasRelatedWork W2026009381 @default.
• W2495109752 hasRelatedWork W2050925112 @default.
• W2495109752 hasRelatedWork W2065343344 @default.
• W2495109752 hasRelatedWork W2163665874 @default.
• W2495109752 hasRelatedWork W2413641859 @default.
• W2495109752 hasRelatedWork W2416831233 @default.

• next