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• W2495182509 endingPage "488" @default.
• W2495182509 startingPage "480" @default.
• W2495182509 abstract "This study aims to evaluate the effects of dietary arginine (Arg) surplus on gilthead sea bream growth, intestinal nutrient absorption capacity, hepatic and intestinal amino acid (AA) metabolism, and oxidative status. For that purpose a 6 weeks growth trial was performed with gilthead sea bream juveniles fed four isolipidic (18%) and isoproteic (44%) diets supplemented with 0, 0.5, 1 and 2% Arg. Dietary Arg did not affect fish growth performance, feed and nitrogen utilization, body composition, and activity of the main AA catabolic enzymes in liver and intestine. Similarly, intestinal nutrient absorption capacity, evaluated by intestinal brush border membrane vesicles technique, was also unaffected by the dietary Arg surplus. On the other hand, enzymatic antioxidant response was modulated by dietary Arg increment, which led to a reduced glutathione peroxidase activity in the liver and the intestine and increased superoxide dismutase activity in the intestine, but did not affect the overall lipid peroxidation values. Some differences in liver and intestine antioxidant enzymatic responses were identified, with the liver showing higher catalase and glucose-6-phosphate dehydrogenase activities, while the intestine presented higher glutathione peroxidase and glutathione reductase activities. Overall, dietary Arg excess showed limited potential to enhance gilthead sea bream performance and intestinal nutrient absorption capacity, but it was shown to modulate hepatic and intestinal antioxidant defences, without affecting overall lipid peroxidation. Recently some fish species have been shown to benefit from dietary arginine surplus, while evidences also exist of an Arg-Lys antagonism in other fish species. This manuscript gives further insight on the potential of dietary arginine supplementation in gilthead sea bream, a major aquaculture species in the Mediterranean." @default.
• W2495182509 created "2016-08-23" @default.
• W2495182509 creator A5019500494 @default.
• W2495182509 creator A5020230896 @default.
• W2495182509 creator A5021374141 @default.
• W2495182509 creator A5030402616 @default.
• W2495182509 creator A5031783121 @default.
• W2495182509 creator A5039260798 @default.
• W2495182509 creator A5041472010 @default.
• W2495182509 creator A5047966838 @default.
• W2495182509 date "2016-11-01" @default.
• W2495182509 modified "2023-09-26" @default.
• W2495182509 title "Dietary arginine surplus does not improve intestinal nutrient absorption capacity, amino acid metabolism and oxidative status of gilthead sea bream (Sparus aurata) juveniles" @default.
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