Matches in SemOpenAlex for { <https://semopenalex.org/work/W2495345741> ?p ?o ?g. }
- W2495345741 endingPage "418" @default.
- W2495345741 startingPage "403" @default.
- W2495345741 abstract "Although at one time a perplexing paradox, coexistent autoimmunity and primary immunodeficiency now stand as two sides of the coin of immunologic dysregulation. In most of the monogenic defects that confer a primary B cell, T cell, or combined immunodeficiency, autoimmunity occurs primarily as a consequence of the impairment of one of more critical checkpoints in the development/maintenance of immunologic self-tolerance. Most importantly, all of these immunodeficiency disorders, even those that are monogenic, can be quite heterogeneous with regard to their clinical phenotype whether or not they are complicated by autoimmunity. Therefore, an understanding of the molecular basis for the nexus between autoimmunity and primary immunodeficiency must await the elucidation of the matrix of factors/mechanisms, which alter gene expression in ways that influence the emergence of these respective clinical phenotypes." @default.
- W2495345741 created "2016-08-23" @default.
- W2495345741 creator A5028142480 @default.
- W2495345741 creator A5083580447 @default.
- W2495345741 date "2014-01-01" @default.
- W2495345741 modified "2023-09-25" @default.
- W2495345741 title "Autoimmunity in Primary Immunodeficiency Disorders" @default.
- W2495345741 cites W1499340535 @default.
- W2495345741 cites W1554199623 @default.
- W2495345741 cites W1568245010 @default.
- W2495345741 cites W1575665885 @default.
- W2495345741 cites W1594237062 @default.
- W2495345741 cites W1966345655 @default.
- W2495345741 cites W1970915931 @default.
- W2495345741 cites W1971734644 @default.
- W2495345741 cites W1978648726 @default.
- W2495345741 cites W1980574246 @default.
- W2495345741 cites W1980690646 @default.
- W2495345741 cites W1981004692 @default.
- W2495345741 cites W1984094695 @default.
- W2495345741 cites W1984146759 @default.
- W2495345741 cites W1986021104 @default.
- W2495345741 cites W2006232263 @default.
- W2495345741 cites W2006725662 @default.
- W2495345741 cites W2008838198 @default.
- W2495345741 cites W2016304443 @default.
- W2495345741 cites W2020930720 @default.
- W2495345741 cites W2024963914 @default.
- W2495345741 cites W2025445218 @default.
- W2495345741 cites W2028650832 @default.
- W2495345741 cites W2033616187 @default.
- W2495345741 cites W2035451300 @default.
- W2495345741 cites W2038413203 @default.
- W2495345741 cites W2040890511 @default.
- W2495345741 cites W2041192609 @default.
- W2495345741 cites W2043651710 @default.
- W2495345741 cites W2047210789 @default.
- W2495345741 cites W2049478216 @default.
- W2495345741 cites W2051906074 @default.
- W2495345741 cites W2053010671 @default.
- W2495345741 cites W2053133856 @default.
- W2495345741 cites W2054145737 @default.
- W2495345741 cites W2055413966 @default.
- W2495345741 cites W2066738217 @default.
- W2495345741 cites W2070638961 @default.
- W2495345741 cites W2071597533 @default.
- W2495345741 cites W2071819199 @default.
- W2495345741 cites W2073716278 @default.
- W2495345741 cites W2083793128 @default.
- W2495345741 cites W2084523295 @default.
- W2495345741 cites W2084527688 @default.
- W2495345741 cites W2086030126 @default.
- W2495345741 cites W2087444519 @default.
- W2495345741 cites W2089996985 @default.
- W2495345741 cites W2090676538 @default.
- W2495345741 cites W2091303626 @default.
- W2495345741 cites W2097615268 @default.
- W2495345741 cites W2100034730 @default.
- W2495345741 cites W2102046770 @default.
- W2495345741 cites W2102352404 @default.
- W2495345741 cites W2105285534 @default.
- W2495345741 cites W2105671517 @default.
- W2495345741 cites W2108270409 @default.
- W2495345741 cites W2113764179 @default.
- W2495345741 cites W2114833837 @default.
- W2495345741 cites W2115016218 @default.
- W2495345741 cites W2115055179 @default.
- W2495345741 cites W2116178189 @default.
- W2495345741 cites W2119070944 @default.
- W2495345741 cites W2121795180 @default.
- W2495345741 cites W2122907933 @default.
- W2495345741 cites W2124369311 @default.
- W2495345741 cites W2126190102 @default.
- W2495345741 cites W2127932958 @default.
- W2495345741 cites W2155246914 @default.
- W2495345741 cites W2157247721 @default.
- W2495345741 cites W2158580948 @default.
- W2495345741 cites W2162224267 @default.
- W2495345741 cites W2165006836 @default.
- W2495345741 cites W2168791265 @default.
- W2495345741 cites W2313774095 @default.
- W2495345741 cites W2315112971 @default.
- W2495345741 cites W2319922476 @default.
- W2495345741 cites W2418616306 @default.
- W2495345741 cites W4211164442 @default.
- W2495345741 doi "https://doi.org/10.1016/b978-0-12-384929-8.00029-0" @default.
- W2495345741 hasPublicationYear "2014" @default.
- W2495345741 type Work @default.
- W2495345741 sameAs 2495345741 @default.
- W2495345741 citedByCount "0" @default.
- W2495345741 crossrefType "book-chapter" @default.
- W2495345741 hasAuthorship W2495345741A5028142480 @default.
- W2495345741 hasAuthorship W2495345741A5083580447 @default.
- W2495345741 hasConcept C104317684 @default.
- W2495345741 hasConcept C127716648 @default.
- W2495345741 hasConcept C203014093 @default.
- W2495345741 hasConcept C2777607303 @default.
- W2495345741 hasConcept C2779019163 @default.