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- W2495352282 abstract "Publisher Summary This chapter describes the in vitro comparison of transfer factor (TF) obtained from skin test positive and negative individuals. The effect of eight preparations of TFdm on lymphocyte proliferation is studied. Five preparations were from donors who were reactive to 5 TU PPD, two from a donor unreactive to 250 TU PPD, and one from a cord blood. All preparations were assayed on recipient cells from persons who were skin test negative to 5 TU PPD and which showed low but variable responses to PPD in vitro as measured by lymphocyte proliferation. CPM from a control blank, where isotope was added immediately before harvest, was subtracted from each test sample before conversion to DPM. The addition of TFdm alone to lymphocyte cultures usually had minimal if any effect on proliferation. TFdm to antigen stimulated lymphocytes appeared to be conditioned by the response of the cultured lymphocytes to antigen alone. It was found that when the differences in the recipient cell reactivity were adjusted by analysis of covariance, TFdm from skin test positive donors could not be distinguished from that of negative donors." @default.
- W2495352282 created "2016-08-23" @default.
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- W2495352282 date "1976-01-01" @default.
- W2495352282 modified "2023-09-26" @default.
- W2495352282 title "IN VITRO COMPARISON OF TFDM OBTAINED FROM SKIN TEST POSITIVE AND NEGATIVE INDIVIDUALS This work was supported by USPHS Grant No. AI-01254-19 and Training Grant No. AI-00005-19." @default.
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- W2495352282 doi "https://doi.org/10.1016/b978-0-12-064650-0.50009-x" @default.
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