FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2495371129> ?p ?o ?g. }

• W2495371129 abstract "Resistance in canine pathogenic staphylococci is necessitating re-evaluation of the current antimicrobial treatments especially for biofilm-associated infections. Long, repeated treatments are often required to control such infections due to the tolerance of bacteria within the biofilm. To comply with the goal of better antibiotic stewardship in veterinary medicine, the efficacies of the available drugs need to be directly assessed on bacterial biofilms. We compared the activities of amoxicillin, cefalexin, clindamycin, doxycycline and marbofloxacin on in vitro biofilms of Staphylococcus pseudintermedius and Staphylococcus aureus. Exposure of biofilms for 15 hours to maximum concentrations of the antibiotics achievable in canine plasma only reduced biofilm bacteria by 0.5 to 2.0 log10 CFU, compared to the control, except for marbofloxacin which reduced S. aureus biofilms by 5.4 log10 CFU. Two-antibiotic combinations did not improve, and even decreased, bacterial killing. In comparison, 5 min-exposure to 2 % chlorhexidine reduced biofilms of the 2 tested strains by 4 log10 CFU. Our results showed that S. pseudintermedius biofilm, unlike S. aureus biofilm, was highly tolerant to all the drugs tested, consistent with the treatment failures observed in practice. Under our conditions, the use of topical chlorhexidine would probably be the best currently available strategy to reduce S. pseudintermedius biofilm." @default.
• W2495371129 created "2016-08-23" @default.
• W2495371129 creator A5027879186 @default.
• W2495371129 creator A5032572523 @default.
• W2495371129 creator A5060602026 @default.
• W2495371129 creator A5069169881 @default.
• W2495371129 date "2016-08-02" @default.
• W2495371129 modified "2023-10-13" @default.
• W2495371129 title "Comparison of the In vitro Activity of Five Antimicrobial Drugs against Staphylococcus pseudintermedius and Staphylococcus aureus Biofilms" @default.
• W2495371129 cites W1529810779 @default.
• W2495371129 cites W1542903983 @default.
• W2495371129 cites W1592345947 @default.
• W2495371129 cites W1600919011 @default.
• W2495371129 cites W1906183726 @default.
• W2495371129 cites W1967816847 @default.
• W2495371129 cites W1973691193 @default.
• W2495371129 cites W1982895251 @default.
• W2495371129 cites W1989942811 @default.
• W2495371129 cites W1994493325 @default.
• W2495371129 cites W1997672020 @default.
• W2495371129 cites W2007464877 @default.
• W2495371129 cites W2009649441 @default.
• W2495371129 cites W2016885239 @default.
• W2495371129 cites W2040686327 @default.
• W2495371129 cites W2045825103 @default.
• W2495371129 cites W2047793287 @default.
• W2495371129 cites W2054378092 @default.
• W2495371129 cites W2057580939 @default.
• W2495371129 cites W2061593007 @default.
• W2495371129 cites W2062837642 @default.
• W2495371129 cites W2063412391 @default.
• W2495371129 cites W2075725260 @default.
• W2495371129 cites W2080936059 @default.
• W2495371129 cites W2102053462 @default.
• W2495371129 cites W2113059183 @default.
• W2495371129 cites W2122580582 @default.
• W2495371129 cites W2125584125 @default.
• W2495371129 cites W2136341269 @default.
• W2495371129 cites W2144440398 @default.
• W2495371129 cites W2154276853 @default.
• W2495371129 cites W2155913518 @default.
• W2495371129 cites W2161483215 @default.
• W2495371129 cites W2309882394 @default.
• W2495371129 cites W2406107337 @default.
• W2495371129 doi "https://doi.org/10.3389/fmicb.2016.01187" @default.
• W2495371129 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4969302" @default.
• W2495371129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27531995" @default.
• W2495371129 hasPublicationYear "2016" @default.
• W2495371129 type Work @default.
• W2495371129 sameAs 2495371129 @default.
• W2495371129 citedByCount "10" @default.
• W2495371129 countsByYear W24953711292017 @default.
• W2495371129 countsByYear W24953711292020 @default.
• W2495371129 countsByYear W24953711292021 @default.
• W2495371129 countsByYear W24953711292022 @default.
• W2495371129 crossrefType "journal-article" @default.
• W2495371129 hasAuthorship W2495371129A5027879186 @default.
• W2495371129 hasAuthorship W2495371129A5032572523 @default.
• W2495371129 hasAuthorship W2495371129A5060602026 @default.
• W2495371129 hasAuthorship W2495371129A5069169881 @default.
• W2495371129 hasBestOaLocation W24953711291 @default.
• W2495371129 hasConcept C2777458120 @default.
• W2495371129 hasConcept C2778756162 @default.
• W2495371129 hasConcept C2778961191 @default.
• W2495371129 hasConcept C2779288629 @default.
• W2495371129 hasConcept C2779489039 @default.
• W2495371129 hasConcept C4937899 @default.
• W2495371129 hasConcept C501593827 @default.
• W2495371129 hasConcept C523546767 @default.
• W2495371129 hasConcept C54355233 @default.
• W2495371129 hasConcept C58123911 @default.
• W2495371129 hasConcept C64778159 @default.
• W2495371129 hasConcept C86803240 @default.
• W2495371129 hasConcept C89423630 @default.
• W2495371129 hasConcept C94665300 @default.
• W2495371129 hasConceptScore W2495371129C2777458120 @default.
• W2495371129 hasConceptScore W2495371129C2778756162 @default.
• W2495371129 hasConceptScore W2495371129C2778961191 @default.
• W2495371129 hasConceptScore W2495371129C2779288629 @default.
• W2495371129 hasConceptScore W2495371129C2779489039 @default.
• W2495371129 hasConceptScore W2495371129C4937899 @default.
• W2495371129 hasConceptScore W2495371129C501593827 @default.
• W2495371129 hasConceptScore W2495371129C523546767 @default.
• W2495371129 hasConceptScore W2495371129C54355233 @default.
• W2495371129 hasConceptScore W2495371129C58123911 @default.
• W2495371129 hasConceptScore W2495371129C64778159 @default.
• W2495371129 hasConceptScore W2495371129C86803240 @default.
• W2495371129 hasConceptScore W2495371129C89423630 @default.
• W2495371129 hasConceptScore W2495371129C94665300 @default.
• W2495371129 hasLocation W24953711291 @default.
• W2495371129 hasLocation W24953711292 @default.
• W2495371129 hasLocation W24953711293 @default.
• W2495371129 hasLocation W24953711294 @default.
• W2495371129 hasLocation W24953711295 @default.
• W2495371129 hasLocation W24953711296 @default.
• W2495371129 hasOpenAccess W2495371129 @default.
• W2495371129 hasPrimaryLocation W24953711291 @default.
• W2495371129 hasRelatedWork W1965369908 @default.
• W2495371129 hasRelatedWork W2037519936 @default.
• W2495371129 hasRelatedWork W2347872938 @default.

• next