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- W2495375195 abstract "Bioinformatics has become a buzzword in the post-genomic era. However, the discipline is not new. This chapter introduces the three scientists whose initiatives 50 years ago led to the birth of the science of bioinformatics, and briefly discusses their contributions. Although at the time it was not called bioinformatics, the application of computers in protein-sequence analysis and tracing protein evolution was the rudimentary form of contemporary bioinformatics. These three scientists were Margaret Dayhoff, Richard Eck, and Robert Ledley. Of these, Margaret Dayhoff’s contributions stood out the most and she is often credited as being the pioneer in bioinformatics for her varied contributions, including developing the first amino-acid substitution matrix for studying protein evolution. The chapter also discusses the scope and tools of bioinformatics." @default.
- W2495375195 created "2016-08-23" @default.
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- W2495375195 date "2014-01-01" @default.
- W2495375195 modified "2023-09-25" @default.
- W2495375195 title "The Beginning of Bioinformatics" @default.
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- W2495375195 doi "https://doi.org/10.1016/b978-0-12-410471-6.00004-9" @default.
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