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- W2495487773 abstract "In the summer of 1977, N. S. Kline and H. E. Lehmann reported their first results with synthetic β-endorphin in psychiatric patients (Kline et al. 1977). They put at our disposal trial material.for six injections and, on the basis of their own findings, advised us to look at possible antidepressive effects during the first hours after the injection. We decided to treat six hospitalized depressive female patients, and we took special care to choose patients whose symptoms had been stable for at least 8 days, so that a sudden change would be noticed immediately. The question was whether a change of the depressive state would occur during the 5 hours after i.v. injection and whether a mania or hypomania could be induced. In addition, we wanted to examine possible changes in body temperature, blood pressure, pulse rate and EEG." @default.
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- W2495487773 date "1979-01-01" @default.
- W2495487773 modified "2023-09-27" @default.
- W2495487773 title "Preliminary results of treatment with β-endorphin in depression" @default.
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- W2495487773 doi "https://doi.org/10.1007/978-1-349-04015-5_47" @default.
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