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• W2495592657 endingPage "55" @default.
• W2495592657 startingPage "27" @default.
• W2495592657 abstract "Immunophenotyping is a technique used to study the protein expressed by cells. This technique is commonly used in basic science research and laboratory diagnostic purpose. This can be done on tissue section (fresh or fixed tissue), and cell suspension. Human cell differentiation molecules (HCDM) is a new terminology coined by the 8th International Workshop on Human Leukocyte Differentiation Antigen (HLDA) to describe surface molecules associated with human cell differentiation. These molecules have been characterized in a series of international workshops studying a large number of monoclonal antibodies. The antibodies have been grouped according to their patterns of reactivity and are referred to as clusters of differentiation (CD). These molecules characterize human leukocytes as well as other human cells such as endothelial and stromal cells. They are not only detected on the surface but also inside the cells. Monoclonal antibodies are routinely used for the diagnosis and classification of hematopoietic malignancies and other hematologic disorders. However by far the vast majority of the available monoclonal antibodies raised against CD molecules are not tumor-specific and react with nonneoplastic hematopoietic cells. These molecules are mostly differentiation associated and not lineage-specific; they may react with nonhematopoietic human cells. Because of these facts, the results of immunophenotypic studies, such as flow cytometry and immunohistochemical stains, should be always incorporated with morphology and other available data, such as cytogenetics and molecular studies." @default.
• W2495592657 created "2016-08-23" @default.
• W2495592657 creator A5061075877 @default.
• W2495592657 date "2008-01-01" @default.
• W2495592657 modified "2023-10-14" @default.
• W2495592657 title "Principles of Immunophenotyping" @default.
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