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- W2495806886 abstract "Hypernatremia is a common condition in emergency medicine, which is associated with high morbidity, and in many conditions is a predictor of excess mortality. The majority of cases of hypernatremia arise secondary to inadequate water intake, often exacerbated by comorbid acute illnesses and excess fluid loss. However, emerging data, particularly from patients in intensive care settings, have shown that significant numbers of hypernatremic patients – up to 50% – may have increased blood volume. Hypernatremia develops due to a combination of increased renal free water clearance due to the impairment of the urine concentrating ability, along with the use of isotonic intravenous fluids. Diabetes insipidus (DI), which results in inappropriate hypotonic polyuria, rarely causes hypernatremia, as the intact thirst mechanism generates sufficient drinking to replace renal water losses. However, if DI is associated with adipsia, diminished conscious levels or vomiting, severe hypernatremia may occur. This chapter will outline the various causes of acute hypernatremia and the correct management of this important condition." @default.
- W2495806886 created "2016-08-23" @default.
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- W2495806886 date "2018-03-02" @default.
- W2495806886 modified "2023-09-26" @default.
- W2495806886 title "Emergency Management of Acute and Chronic Hypernatremia" @default.
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- W2495806886 doi "https://doi.org/10.1002/9781119374800.ch42" @default.
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