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- W2496085280 endingPage "81" @default.
- W2496085280 startingPage "73" @default.
- W2496085280 abstract "Interferon (IFN)-γ is the uppermost cytokine implicated in anti-tumor immunity. With its cytostatic, pro-apoptotic and immune-provoking effects, IFN-γ plays a central role in the recognition and elimination of transformed cells. Considering well-characterized anti-tumor effects of this cytokine, many clinical trials and immunotherapy approaches have been designed to reinforce IFN-γ-mediated immunity for different types of cancer. However, the outcomes were not satisfactory and leaded to questioning of alternative actions of IFN-γ. Many regulatory pathways can be induced by IFN-γ to protect the normal tissues from collateral damage and to facilitate the re-establishment of homeostasis. Nevertheless, malignant cells can take the advantage of IFN-γ as an inducer of mediators inhibiting anti-tumor immune reactions. In addition, under the influence of tumor-derived factors, certain types of immune cells are also licensed by IFN-γ to perform regulatory actions. This review focuses on the immune modulatory functions of IFN-γ in cancer as an alternative story to be told." @default.
- W2496085280 created "2016-08-23" @default.
- W2496085280 creator A5018695217 @default.
- W2496085280 creator A5041355015 @default.
- W2496085280 date "2016-10-01" @default.
- W2496085280 modified "2023-10-16" @default.
- W2496085280 title "The untold story of IFN-γ in cancer biology" @default.
- W2496085280 cites W1479844134 @default.
- W2496085280 cites W1489515520 @default.
- W2496085280 cites W1500124513 @default.
- W2496085280 cites W1505088803 @default.
- W2496085280 cites W1510578593 @default.
- W2496085280 cites W1529167990 @default.
- W2496085280 cites W1530235393 @default.
- W2496085280 cites W1551156084 @default.
- W2496085280 cites W1557111800 @default.
- W2496085280 cites W1561606382 @default.
- W2496085280 cites W1571428739 @default.
- W2496085280 cites W1574615823 @default.
- W2496085280 cites W1590342103 @default.
- W2496085280 cites W1597332663 @default.
- W2496085280 cites W1601314558 @default.
- W2496085280 cites W160271021 @default.
- W2496085280 cites W1603862958 @default.
- W2496085280 cites W1626408469 @default.
- W2496085280 cites W1630281638 @default.
- W2496085280 cites W1637209605 @default.
- W2496085280 cites W1671722457 @default.
- W2496085280 cites W1749876116 @default.
- W2496085280 cites W1797677206 @default.
- W2496085280 cites W1798655419 @default.
- W2496085280 cites W1798713465 @default.
- W2496085280 cites W1839288048 @default.
- W2496085280 cites W1839349418 @default.
- W2496085280 cites W1905951047 @default.
- W2496085280 cites W1921318307 @default.
- W2496085280 cites W1925817305 @default.
- W2496085280 cites W1933912253 @default.
- W2496085280 cites W1938148688 @default.
- W2496085280 cites W1957985734 @default.
- W2496085280 cites W1963728529 @default.
- W2496085280 cites W1964173702 @default.
- W2496085280 cites W1964596502 @default.
- W2496085280 cites W1965598536 @default.
- W2496085280 cites W1966577330 @default.
- W2496085280 cites W1967863535 @default.
- W2496085280 cites W1968732608 @default.
- W2496085280 cites W1970506485 @default.
- W2496085280 cites W1970786645 @default.
- W2496085280 cites W1971425687 @default.
- W2496085280 cites W1972648258 @default.
- W2496085280 cites W1974417303 @default.
- W2496085280 cites W1977927677 @default.
- W2496085280 cites W1983150631 @default.
- W2496085280 cites W1985579610 @default.
- W2496085280 cites W1991199641 @default.
- W2496085280 cites W1991467181 @default.
- W2496085280 cites W1992045882 @default.
- W2496085280 cites W1994568522 @default.
- W2496085280 cites W1994815971 @default.
- W2496085280 cites W1994993231 @default.
- W2496085280 cites W1995646065 @default.
- W2496085280 cites W1996032846 @default.
- W2496085280 cites W1996377947 @default.
- W2496085280 cites W1998810112 @default.
- W2496085280 cites W2000417157 @default.
- W2496085280 cites W2007309728 @default.
- W2496085280 cites W2009592484 @default.
- W2496085280 cites W2010761042 @default.
- W2496085280 cites W2015706998 @default.
- W2496085280 cites W2019214729 @default.
- W2496085280 cites W2021289499 @default.
- W2496085280 cites W2021472371 @default.
- W2496085280 cites W2021967439 @default.
- W2496085280 cites W2022580424 @default.
- W2496085280 cites W2026318599 @default.
- W2496085280 cites W2027069370 @default.
- W2496085280 cites W2028107828 @default.
- W2496085280 cites W2029498694 @default.
- W2496085280 cites W2030995912 @default.
- W2496085280 cites W2032780125 @default.
- W2496085280 cites W2032900167 @default.
- W2496085280 cites W2034750454 @default.
- W2496085280 cites W2036930922 @default.
- W2496085280 cites W2037299986 @default.
- W2496085280 cites W2038107832 @default.
- W2496085280 cites W2038181603 @default.
- W2496085280 cites W2038675789 @default.
- W2496085280 cites W2039123767 @default.
- W2496085280 cites W2039147606 @default.
- W2496085280 cites W2039370099 @default.
- W2496085280 cites W2039817645 @default.
- W2496085280 cites W2040580977 @default.
- W2496085280 cites W2042092652 @default.
- W2496085280 cites W2047180710 @default.
- W2496085280 cites W2047199931 @default.
- W2496085280 cites W2048607324 @default.
- W2496085280 cites W2050317788 @default.