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- W2496158102 abstract "This chapter focuses on pesticide percutaneous absorption and decontamination, and its major processes and outcomes. Human skin is a primary body organ that contacts the environment and is a route by which pesticides enter the body. Human skin is designed to retain body fluids and act as a barrier to the environment. This barrier can be crossed by a process called percutaneous absorption. It is a primary focal point for dermatotoxicology and dermatopharmacology. Local and systemic toxicity depend on a chemical penetrating the skin. The skin is both a barrier to absorption and a primary route to the systemic circulation. The major processes of estimating absorption are: biological or pharmacological response; in vitro methodology; skin flaps, and stripping method. Human absorption differs in regions of the body, and clothing can be a partial barrier. However, pesticides have managed to cross those barriers, leading to illness and death. Although decontamination of a chemical from the skin is commonly done by washing with soap and water, recent evidence suggests that the skin and the body are often unknowingly subjected to enhanced penetration and systemic absorption or toxicity because the decontamination procedure does not work or may actually enhance absorption." @default.
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- W2496158102 date "2001-01-01" @default.
- W2496158102 modified "2023-09-26" @default.
- W2496158102 title "Pesticide Percutaneous Absorption and Decontamination" @default.
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- W2496158102 doi "https://doi.org/10.1016/b978-012426260-7.50046-x" @default.
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