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- W2496231646 endingPage "R454" @default.
- W2496231646 startingPage "R437" @default.
- W2496231646 abstract "Hypertension is a common medical condition and affects approximately 20% of the population in developed countries. Primary aldosteronism is the most common form of secondary hypertension and affects 8–13% of patients with hypertension. The two most common causes of primary aldosteronism are aldosterone-producing adenoma and bilateral adrenal hyperplasia. Familial hyperaldosteronism types I, II and III are the known genetic syndromes, in which both adrenal glands produce excessive amounts of aldosterone. However, only a minority of patients with primary aldosteronism have one of these syndromes. Several novel susceptibility genes have been found to be mutated in aldosterone-producing adenomas: KCNJ5 , ATP1A1 , ATP2B3 , CTNNB1, CACNA1D, CACNA1H and ARMC5 . This review describes the genes currently known to be responsible for primary aldosteronism, discusses the origin of aldosterone-producing adenomas and considers the future clinical implications based on these novel insights." @default.
- W2496231646 created "2016-08-23" @default.
- W2496231646 creator A5004819403 @default.
- W2496231646 creator A5035985085 @default.
- W2496231646 creator A5048249385 @default.
- W2496231646 date "2016-10-01" @default.
- W2496231646 modified "2023-09-26" @default.
- W2496231646 title "Genetics of primary hyperaldosteronism" @default.
- W2496231646 cites W1523500733 @default.
- W2496231646 cites W1619288742 @default.
- W2496231646 cites W1885172161 @default.
- W2496231646 cites W1903925553 @default.
- W2496231646 cites W1907427644 @default.
- W2496231646 cites W1967137553 @default.
- W2496231646 cites W1967440935 @default.
- W2496231646 cites W1968925586 @default.
- W2496231646 cites W1971085650 @default.
- W2496231646 cites W1971279293 @default.
- W2496231646 cites W1975394549 @default.
- W2496231646 cites W1978100432 @default.
- W2496231646 cites W1979069430 @default.
- W2496231646 cites W1981486350 @default.
- W2496231646 cites W1983210215 @default.
- W2496231646 cites W1983803713 @default.
- W2496231646 cites W1985327924 @default.
- W2496231646 cites W1985858914 @default.
- W2496231646 cites W1986219588 @default.
- W2496231646 cites W1991449126 @default.
- W2496231646 cites W1992240882 @default.
- W2496231646 cites W2000483635 @default.
- W2496231646 cites W2001722277 @default.
- W2496231646 cites W2003456330 @default.
- W2496231646 cites W2005329916 @default.
- W2496231646 cites W2005865177 @default.
- W2496231646 cites W2008821347 @default.
- W2496231646 cites W2016170962 @default.
- W2496231646 cites W2019716888 @default.
- W2496231646 cites W2022614248 @default.
- W2496231646 cites W2022880162 @default.
- W2496231646 cites W2024167026 @default.
- W2496231646 cites W2025200846 @default.
- W2496231646 cites W2029767886 @default.
- W2496231646 cites W2037070147 @default.
- W2496231646 cites W2037296473 @default.
- W2496231646 cites W2040928761 @default.
- W2496231646 cites W2042806276 @default.
- W2496231646 cites W2045591523 @default.
- W2496231646 cites W2048712799 @default.
- W2496231646 cites W2057934269 @default.
- W2496231646 cites W2059496396 @default.
- W2496231646 cites W2061341378 @default.
- W2496231646 cites W2063070371 @default.
- W2496231646 cites W2070818730 @default.
- W2496231646 cites W2071497196 @default.
- W2496231646 cites W2076757207 @default.
- W2496231646 cites W2082398062 @default.
- W2496231646 cites W2089400376 @default.
- W2496231646 cites W2094349878 @default.
- W2496231646 cites W2096701787 @default.
- W2496231646 cites W2099488003 @default.
- W2496231646 cites W2100537280 @default.
- W2496231646 cites W2100690266 @default.
- W2496231646 cites W2101961791 @default.
- W2496231646 cites W2107964427 @default.
- W2496231646 cites W2108644248 @default.
- W2496231646 cites W2110420469 @default.
- W2496231646 cites W2111582520 @default.
- W2496231646 cites W2114750007 @default.
- W2496231646 cites W2120245762 @default.
- W2496231646 cites W2120347052 @default.
- W2496231646 cites W2123314654 @default.
- W2496231646 cites W2125130269 @default.
- W2496231646 cites W2125261314 @default.
- W2496231646 cites W2126663691 @default.
- W2496231646 cites W2137314174 @default.
- W2496231646 cites W2141197851 @default.
- W2496231646 cites W2145316463 @default.
- W2496231646 cites W2146136214 @default.
- W2496231646 cites W2147066085 @default.
- W2496231646 cites W2153316394 @default.
- W2496231646 cites W2154579353 @default.
- W2496231646 cites W2154704880 @default.
- W2496231646 cites W2154788287 @default.
- W2496231646 cites W2156903075 @default.
- W2496231646 cites W2157610967 @default.
- W2496231646 cites W2157801554 @default.
- W2496231646 cites W2159980848 @default.
- W2496231646 cites W2160612644 @default.
- W2496231646 cites W2162975882 @default.
- W2496231646 cites W2163435696 @default.
- W2496231646 cites W2170896657 @default.
- W2496231646 cites W2178916197 @default.
- W2496231646 cites W2282891373 @default.
- W2496231646 cites W2320400149 @default.
- W2496231646 cites W2332657075 @default.
- W2496231646 cites W2336613908 @default.
- W2496231646 cites W2395055006 @default.
- W2496231646 cites W2412941099 @default.