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• W2496326893 endingPage "387" @default.
• W2496326893 startingPage "365" @default.
• W2496326893 abstract "The enterobacteriaceae family consists of 41 genera of gram-negative, facultatively anaerobic bacteria. Many of the organisms are normal inhabitants of the gastrointestinal tract of animals, however, several are identified as primary or opportunistic pathogens. Of these, only a few are documented to cause spontaneous disease in laboratory mice. Salmonella has historically been a concern in mouse facilities due, in part, to its zoonotic potential, but with the increased standards of sanitation and husbandry practiced in most laboratory animal facilities today, natural outbreaks of salmonellosis are rare. Escherichia, the type genus, includes strains capable of causing disease in humans and domestic animal species, yet mice are largely resistant to infection with pathogenic strains of escherichia coli. However, immunodeficient mice are susceptible to infection and disease caused by certain lactose non-fermenting strains. A related organism, citrobacter rodentium, is highly pathogenic, particularly in young mice, but like salmonella, it is excluded from most barrier facilities today. The mechanism responsible for the relative resistance of immunocompetent mice to infection with pathogenic enteric organisms is unclear but would seem to involve more than simply appropriate innate and/or adaptive immune responses. It may be that laboratory mice lack suitable receptors for bacterial attachment that are expressed on cells of host species that are susceptible to infection." @default.
• W2496326893 created "2016-08-23" @default.
• W2496326893 creator A5081614923 @default.
• W2496326893 creator A5084039634 @default.
• W2496326893 date "2007-01-01" @default.
• W2496326893 modified "2023-10-16" @default.
• W2496326893 title "Enterobacteriaceae Pseudomonas aeruginosa and Streptobacillus moniliformis" @default.
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