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- W24965357 abstract "Publisher Summary Studies indicate that physical destruction of the serotonin (5-HT)-containing neurons of the raphe nuclei or chemical interference of biosynthesis of 5-HT causes total or partial insomnia in the cat. These studies together with other supportive evidence mean that at least some of the neurons that use 5-HT as their neurotransmitter play a role in sleep. To obtain an understanding of the events involving serotonin during natural sleep, cats were killed at a specified stage of sleep and the serotonin content of regional brain was measured. A transient decrease in serotonin content within a time period shorter than its half-life, however, may be due to an increase in the rate of release of the neurotransmitter. The decrease of cerebral cortical 5-HT after 10 minutes of nonrapid eye movement (NREM) sleep would have taken place because this change is brought about by a massive release of serotonin, likely as a result of an increase in impulse traffic over serotonergic synapses during the specified time." @default.
- W24965357 created "2016-06-24" @default.
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- W24965357 date "1973-01-01" @default.
- W24965357 modified "2023-10-18" @default.
- W24965357 title "CAT BRAIN SEROTONIN CONTENT DURING SLEEP AND WAKEFULNESS" @default.
- W24965357 doi "https://doi.org/10.1016/b978-0-12-078150-8.50055-4" @default.
- W24965357 hasPublicationYear "1973" @default.
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