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- W2496603251 abstract "Abstract The most fundamental piece of knowledge about any protein or metabolite is its identity. Regardless of the type of analytical method used to measure proteins and metabolites, the result is a signal provided by a protein or metabolite. If these signals cannot be assigned to a specific molecule, the measurement is of little value. In previous eras, when most studies focused on only a few molecules per experiment, molecular identification was accomplished through comparison with standards. Today, when thousands of signals are recorded in mass spectrometry-based proteomic and metabolomic experiments, trying to identify as many of these molecules has become a major effort. Fortunately, the development of high-performance mass spectrometers and sophisticated software algorithms has enabled broad identification of hundreds, and in some cases thousands, of proteins and metabolites in single experiments. This chapter describes some of the approaches used to identify analytical signals acquired during proteomic and metabolite studies." @default.
- W2496603251 created "2016-08-23" @default.
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- W2496603251 date "2013-01-01" @default.
- W2496603251 modified "2023-09-25" @default.
- W2496603251 title "Protein and Metabolite Identification" @default.
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- W2496603251 doi "https://doi.org/10.1016/b978-0-12-394446-7.00016-9" @default.
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