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- W2496648756 abstract "Background: The present study was designed to evaluate effectiveness of 1.2% atorvastatin (ATV) gel, as an adjunct to scaling and root planing (SRP) in the treatment of intrabony defects in chronic periodontitis (CP) in patients with type 2 diabetes mellitus (t2DM). Methods: Seventy‐five patients were categorized into two treatment groups: 1) SRP plus 1.2% ATV and 2) SRP plus placebo. Clinical parameters including modified sulcus bleeding index, probing depth (PD), and relative attachment level (RAL) were recorded at baseline and 3, 6, and 9 months. Percentage radiographic defect depth reduction was evaluated using computer‐aided software at baseline and 6 and 9 months. Results: Mean PD reduction and mean RAL gain was greater in the ATV group than the placebo group at 3, 6, and 9 months. Furthermore, ATV group sites presented with a significantly greater percentage of radiographic defect depth reduction at 6 and 9 months. Conclusion: Locally delivered ATV was found to be effective in treatment of intrabony defects in CP in patients with t2DM." @default.
- W2496648756 created "2016-08-23" @default.
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- W2496648756 date "2016-11-01" @default.
- W2496648756 modified "2023-09-23" @default.
- W2496648756 title "Efficacy of Subgingivally Delivered 1.2% Atorvastatin in the Treatment of Chronic Periodontitis in Patients With Type 2 Diabetes Mellitus: A Randomized Controlled Clinical Trial" @default.
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- W2496648756 doi "https://doi.org/10.1902/jop.2016.130227" @default.
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