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- W2497100150 abstract "The main components of a capillary electrophoresis (CE) instrument are power supply, injection system, capillary, detector, and buffer vials. The final electropherogram looks similar to a chromatogram obtained from high-performance liquid chromatography (HPLC). The majority of the literature using CE describes the application of ultraviolet (UV) or fluorescence detection because these were the only detectors offered by the early commercial instrument manufacturers. Next-generation instruments offer conductivity and mass spectrometry detection in addition to fluorescence and UV detection; therefore, applications using these detectors are no longer limited to university research departments. One of the major differences among commercially available instruments is the approach to cooling the capillary; the options include liquid cooling, forced air-nitrogen convection, and no mechanical circulation. Liquid cooling provides the most control, but forced air-nitrogen is sufficient for the purposes of reproducibility. Capillary cooling is of the most importance when using high ionic strength buffers and high voltages." @default.
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- W2497100150 date "1997-01-01" @default.
- W2497100150 modified "2023-10-16" @default.
- W2497100150 title "Instrumentation for Capillary Electrophoresis" @default.
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- W2497100150 doi "https://doi.org/10.1016/b978-012136640-7/50006-4" @default.
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