Matches in SemOpenAlex for { <https://semopenalex.org/work/W2498045495> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W2498045495 endingPage "777" @default.
- W2498045495 startingPage "767" @default.
- W2498045495 abstract "The profiles of DNA fragments, generated by a restriction endonuclease BamHI, in the unique regions of herpes simplex virus type 1 (HSV-1) were compared among seven substrains originally derived from the parental Miyama strain. These substrains consist of five CPE variants (-GCr, -GCf, +GC (LPV), +GC (SPV) and +GC (81)) and two descendent strains of -GCr (αV and βV), both recovered from persistently infected L cell cultures originally established with -GCr.Some heterogeneous fragments were recognized among the seven substrains. The Southern blot hybridization analysis, using the subcloned DNA fragments of -GCr as probes, revealed the loss of the cleavage site between BamHI-T and BamHI-J' fragments in one of these substrains, αV. In vitro viral reproduction in an enormous number of cycles, which took place for a long period of 14 years in a persistently infected culture, might cause occasional spontaneous mutations of the virus carried in this culture and result in the loss of the cleavage site in the unique region of its genome." @default.
- W2498045495 created "2016-08-23" @default.
- W2498045495 creator A5033453155 @default.
- W2498045495 date "1990-06-01" @default.
- W2498045495 modified "2023-09-23" @default.
- W2498045495 title "単純ヘルペスウイルス1型in vitro長期持続感染株のゲノムに認められたBamHI-T, J'両断片間の制限酵素切断点の欠失" @default.
- W2498045495 hasPublicationYear "1990" @default.
- W2498045495 type Work @default.
- W2498045495 sameAs 2498045495 @default.
- W2498045495 citedByCount "0" @default.
- W2498045495 crossrefType "journal-article" @default.
- W2498045495 hasAuthorship W2498045495A5033453155 @default.
- W2498045495 hasConcept C104317684 @default.
- W2498045495 hasConcept C128319531 @default.
- W2498045495 hasConcept C130123407 @default.
- W2498045495 hasConcept C133307689 @default.
- W2498045495 hasConcept C141231307 @default.
- W2498045495 hasConcept C151730666 @default.
- W2498045495 hasConcept C153911025 @default.
- W2498045495 hasConcept C159047783 @default.
- W2498045495 hasConcept C170673058 @default.
- W2498045495 hasConcept C175156509 @default.
- W2498045495 hasConcept C2522874641 @default.
- W2498045495 hasConcept C2781196997 @default.
- W2498045495 hasConcept C3017666073 @default.
- W2498045495 hasConcept C42174275 @default.
- W2498045495 hasConcept C43369102 @default.
- W2498045495 hasConcept C54355233 @default.
- W2498045495 hasConcept C552990157 @default.
- W2498045495 hasConcept C84289048 @default.
- W2498045495 hasConcept C86803240 @default.
- W2498045495 hasConceptScore W2498045495C104317684 @default.
- W2498045495 hasConceptScore W2498045495C128319531 @default.
- W2498045495 hasConceptScore W2498045495C130123407 @default.
- W2498045495 hasConceptScore W2498045495C133307689 @default.
- W2498045495 hasConceptScore W2498045495C141231307 @default.
- W2498045495 hasConceptScore W2498045495C151730666 @default.
- W2498045495 hasConceptScore W2498045495C153911025 @default.
- W2498045495 hasConceptScore W2498045495C159047783 @default.
- W2498045495 hasConceptScore W2498045495C170673058 @default.
- W2498045495 hasConceptScore W2498045495C175156509 @default.
- W2498045495 hasConceptScore W2498045495C2522874641 @default.
- W2498045495 hasConceptScore W2498045495C2781196997 @default.
- W2498045495 hasConceptScore W2498045495C3017666073 @default.
- W2498045495 hasConceptScore W2498045495C42174275 @default.
- W2498045495 hasConceptScore W2498045495C43369102 @default.
- W2498045495 hasConceptScore W2498045495C54355233 @default.
- W2498045495 hasConceptScore W2498045495C552990157 @default.
- W2498045495 hasConceptScore W2498045495C84289048 @default.
- W2498045495 hasConceptScore W2498045495C86803240 @default.
- W2498045495 hasLocation W24980454951 @default.
- W2498045495 hasOpenAccess W2498045495 @default.
- W2498045495 hasPrimaryLocation W24980454951 @default.
- W2498045495 hasVolume "102" @default.
- W2498045495 isParatext "false" @default.
- W2498045495 isRetracted "false" @default.
- W2498045495 magId "2498045495" @default.
- W2498045495 workType "article" @default.