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- W2498201107 abstract "Some axons exhibit subthreshold oscillations and some dendrites propagate spikes, neither of which would occur if the membranes are purely passive. This chapter discusses these phenomena. Depending on membrane properties and stimulus strength, the subthreshold response of an axon could be either as predicted by the cable equations or in the form of a damped oscillation. Such oscillations could be computed for the space-clamped axon by using a linearized approximation of their model. The chapter discusses graded pulses (g-pulses) that may be of importance for signal transmission in dendrites and other fibers, where they could be propagated over long distances without complete attenuation. Because they are less refractory than all-or-none spikes, g-pulses can be summated more flexibly. They represent a whole range of signals from the nondecremental action potential to electrotonic responses, combining flexibility and reliability to varying degrees. The study of g-pulses under varying degrees of regeneration should help in elucidating the molecular basis of membrane excitability." @default.
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- W2498201107 date "1972-01-01" @default.
- W2498201107 modified "2023-09-23" @default.
- W2498201107 title "GRADED RESPONSES IN ACTIVE MEMBRANES" @default.
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