Matches in SemOpenAlex for { <https://semopenalex.org/work/W24984958> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W24984958 endingPage "1375" @default.
- W24984958 startingPage "1367" @default.
- W24984958 abstract "The lack of a reproducible method for the production of thin tissue slices has hindered the use of liver slices as an in vitro tool for hepatotoxicity studies. Fresh human, rat, and rabbit liver was processed using a mechanical slicer. With this instrument, precision (5% of thickness) liver slices in the submillimeter range could be produced at a rapid rate. Slices were prepared from fresh livers in chilled, oxygenated buffer to minimize trauma. Following incubation for up to 20 h in a dynamic organ culture system, histology of incubated slices suggested that 250 m precision-cut slices were optimum in regard to morphology relative to liver slices incubated under conventional organ culture conditions. Addition of bromobenzene to the culture showed time-dependent hepatotoxicity based on two classic parameters of cell degeneration. Histological evidence is presented which suggests the usefulness of this system for hepatotoxicity studies and the production of focal necrosis in vitro." @default.
- W24984958 created "2016-06-24" @default.
- W24984958 creator A5024842461 @default.
- W24984958 creator A5028679979 @default.
- W24984958 creator A5059016819 @default.
- W24984958 creator A5070357295 @default.
- W24984958 creator A5078462199 @default.
- W24984958 creator A5078768251 @default.
- W24984958 creator A5091173043 @default.
- W24984958 date "1985-04-01" @default.
- W24984958 modified "2023-10-14" @default.
- W24984958 title "Dynamic organ culture of precision liver slices for toxicology" @default.
- W24984958 cites W1597011288 @default.
- W24984958 cites W1971557513 @default.
- W24984958 cites W1986870555 @default.
- W24984958 cites W1988450658 @default.
- W24984958 cites W1990498836 @default.
- W24984958 cites W2016604558 @default.
- W24984958 cites W2050992444 @default.
- W24984958 cites W2078000194 @default.
- W24984958 cites W93751334 @default.
- W24984958 doi "https://doi.org/10.1016/0024-3205(85)90042-6" @default.
- W24984958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3982217" @default.
- W24984958 hasPublicationYear "1985" @default.
- W24984958 type Work @default.
- W24984958 sameAs 24984958 @default.
- W24984958 citedByCount "128" @default.
- W24984958 countsByYear W249849582012 @default.
- W24984958 countsByYear W249849582013 @default.
- W24984958 countsByYear W249849582015 @default.
- W24984958 countsByYear W249849582016 @default.
- W24984958 countsByYear W249849582017 @default.
- W24984958 countsByYear W249849582018 @default.
- W24984958 countsByYear W249849582019 @default.
- W24984958 countsByYear W249849582020 @default.
- W24984958 countsByYear W249849582021 @default.
- W24984958 countsByYear W249849582022 @default.
- W24984958 countsByYear W249849582023 @default.
- W24984958 crossrefType "journal-article" @default.
- W24984958 hasAuthorship W24984958A5024842461 @default.
- W24984958 hasAuthorship W24984958A5028679979 @default.
- W24984958 hasAuthorship W24984958A5059016819 @default.
- W24984958 hasAuthorship W24984958A5070357295 @default.
- W24984958 hasAuthorship W24984958A5078462199 @default.
- W24984958 hasAuthorship W24984958A5078768251 @default.
- W24984958 hasAuthorship W24984958A5091173043 @default.
- W24984958 hasConcept C142724271 @default.
- W24984958 hasConcept C161790260 @default.
- W24984958 hasConcept C185592680 @default.
- W24984958 hasConcept C202751555 @default.
- W24984958 hasConcept C25642318 @default.
- W24984958 hasConcept C2776946247 @default.
- W24984958 hasConcept C28483552 @default.
- W24984958 hasConcept C503630168 @default.
- W24984958 hasConcept C55493867 @default.
- W24984958 hasConcept C57742111 @default.
- W24984958 hasConcept C71924100 @default.
- W24984958 hasConcept C86803240 @default.
- W24984958 hasConcept C90703135 @default.
- W24984958 hasConceptScore W24984958C142724271 @default.
- W24984958 hasConceptScore W24984958C161790260 @default.
- W24984958 hasConceptScore W24984958C185592680 @default.
- W24984958 hasConceptScore W24984958C202751555 @default.
- W24984958 hasConceptScore W24984958C25642318 @default.
- W24984958 hasConceptScore W24984958C2776946247 @default.
- W24984958 hasConceptScore W24984958C28483552 @default.
- W24984958 hasConceptScore W24984958C503630168 @default.
- W24984958 hasConceptScore W24984958C55493867 @default.
- W24984958 hasConceptScore W24984958C57742111 @default.
- W24984958 hasConceptScore W24984958C71924100 @default.
- W24984958 hasConceptScore W24984958C86803240 @default.
- W24984958 hasConceptScore W24984958C90703135 @default.
- W24984958 hasIssue "14" @default.
- W24984958 hasLocation W249849581 @default.
- W24984958 hasLocation W249849582 @default.
- W24984958 hasOpenAccess W24984958 @default.
- W24984958 hasPrimaryLocation W249849581 @default.
- W24984958 hasRelatedWork W1510532419 @default.
- W24984958 hasRelatedWork W151164801 @default.
- W24984958 hasRelatedWork W188252109 @default.
- W24984958 hasRelatedWork W2082728095 @default.
- W24984958 hasRelatedWork W2085834705 @default.
- W24984958 hasRelatedWork W2225973999 @default.
- W24984958 hasRelatedWork W2324018786 @default.
- W24984958 hasRelatedWork W2352740403 @default.
- W24984958 hasRelatedWork W2406906088 @default.
- W24984958 hasRelatedWork W2549956872 @default.
- W24984958 hasVolume "36" @default.
- W24984958 isParatext "false" @default.
- W24984958 isRetracted "false" @default.
- W24984958 magId "24984958" @default.
- W24984958 workType "article" @default.