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- W2498536005 abstract "The ascertained prevalence of Huntington's disease (HD) increased significantly following the provision of diagnostic testing. A systematic review was conducted to estimate the prevalence of HD in the post-diagnostic testing era. 22 studies with original data pertaining to the prevalence of HD (1993–2015) were included and analyzed. A global meta-analysis was not performed due to heterogeneity in study methods and geographical variation. The prevalence of HD is significantly lower in Asian populations compared with western Europe, North America and Australia. The global variation in HD prevalence is partly explained by the average CAG repeat lengths and frequency of different HTT gene haplotypes in the general population. Understanding the prevalence of HD has significant implications for healthcare resource planning." @default.
- W2498536005 created "2016-08-23" @default.
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- W2498536005 date "2016-08-01" @default.
- W2498536005 modified "2023-10-11" @default.
- W2498536005 title "The global prevalence of Huntington's disease: a systematic review and discussion" @default.
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- W2498536005 doi "https://doi.org/10.2217/nmt-2016-0008" @default.
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