Matches in SemOpenAlex for { <https://semopenalex.org/work/W2498903669> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2498903669 endingPage "83" @default.
- W2498903669 startingPage "75" @default.
- W2498903669 abstract "Recent studies have demonstrated the activation of coagulation pathways in asthmatic airways. This study aimed to determine systemic blood coagulation during asthma exacerbation compared with the stable state in children.Pediatric patients (aged between 5 and 15 years) suffering from asthma exacerbation were enrolled. von Willebrand factor (vWF), plasminogen activator inhibitor type-1 (PAI-1), protein C, D-dimer, prothrombin fragment 1 + 2 (F1 + 2), thrombin-antithrombin complex (TAT), and C-reactive protein (CRP) levels were measured during asthma exacerbation and stable state.A total of 22 patients were enrolled. The median vWF, PAI-1, and CRP during asthma exacerbation were significantly higher than those of the stable state: 147.5% (interquartile range, IQR: 111.05-196.57) versus 94% (IQR: 69.72-109.62, p < 0.001), 41.9 ng/ml (IQR: 21.91-48.61) versus 26.17 ng/ml (IQR: 15.89-34.44, p < 0.03), and 4.46 mg/l (IQR: 2.15-16.23) versus 0.87 mg/l (IQR: 0.20-3.89, p < 0.015), respectively. However, the median protein C during asthma exacerbation was significantly lower than that of the stable state: 99.5% (IQR: 86.75-117) versus 113% (IQR: 94-115.25), p = 0.01. No significant difference was found between the levels of D-dimer, F1 + 2, and TAT during asthma exacerbation and stable state. Ultimately, D-dimer was positively correlated with asthma exacerbation score (R = 0.466, p = 0.027). A significant correlation was observed between vWF and CRP (R = 0.527, p = 0.012).Evidence was found of increased endothelial activation and increased PAI-1 during asthma exacerbation. This may emphasize the potential role of blood coagulation in asthma exacerbation." @default.
- W2498903669 created "2016-08-23" @default.
- W2498903669 creator A5013394134 @default.
- W2498903669 creator A5033742371 @default.
- W2498903669 creator A5039831809 @default.
- W2498903669 creator A5059122892 @default.
- W2498903669 creator A5065838216 @default.
- W2498903669 creator A5069953991 @default.
- W2498903669 creator A5081097595 @default.
- W2498903669 date "2016-01-01" @default.
- W2498903669 modified "2023-10-16" @default.
- W2498903669 title "Blood Coagulation and Asthma Exacerbation in Children" @default.
- W2498903669 cites W1685198220 @default.
- W2498903669 cites W1709699037 @default.
- W2498903669 cites W1979861040 @default.
- W2498903669 cites W1981828502 @default.
- W2498903669 cites W1989528047 @default.
- W2498903669 cites W2010934830 @default.
- W2498903669 cites W2022387905 @default.
- W2498903669 cites W2044941131 @default.
- W2498903669 cites W2052812481 @default.
- W2498903669 cites W2057642842 @default.
- W2498903669 cites W2078103564 @default.
- W2498903669 cites W2145415637 @default.
- W2498903669 cites W2912349604 @default.
- W2498903669 doi "https://doi.org/10.1159/000446775" @default.
- W2498903669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27454316" @default.
- W2498903669 hasPublicationYear "2016" @default.
- W2498903669 type Work @default.
- W2498903669 sameAs 2498903669 @default.
- W2498903669 citedByCount "9" @default.
- W2498903669 countsByYear W24989036692019 @default.
- W2498903669 countsByYear W24989036692020 @default.
- W2498903669 countsByYear W24989036692021 @default.
- W2498903669 countsByYear W24989036692022 @default.
- W2498903669 countsByYear W24989036692023 @default.
- W2498903669 crossrefType "journal-article" @default.
- W2498903669 hasAuthorship W2498903669A5013394134 @default.
- W2498903669 hasAuthorship W2498903669A5033742371 @default.
- W2498903669 hasAuthorship W2498903669A5039831809 @default.
- W2498903669 hasAuthorship W2498903669A5059122892 @default.
- W2498903669 hasAuthorship W2498903669A5065838216 @default.
- W2498903669 hasAuthorship W2498903669A5069953991 @default.
- W2498903669 hasAuthorship W2498903669A5081097595 @default.
- W2498903669 hasBestOaLocation W24989036691 @default.
- W2498903669 hasConcept C119060515 @default.
- W2498903669 hasConcept C126322002 @default.
- W2498903669 hasConcept C203014093 @default.
- W2498903669 hasConcept C2776042228 @default.
- W2498903669 hasConcept C2776914184 @default.
- W2498903669 hasConcept C2777014857 @default.
- W2498903669 hasConcept C2778382381 @default.
- W2498903669 hasConcept C2779394231 @default.
- W2498903669 hasConcept C2779519742 @default.
- W2498903669 hasConcept C2781195455 @default.
- W2498903669 hasConcept C71924100 @default.
- W2498903669 hasConcept C89560881 @default.
- W2498903669 hasConcept C90924648 @default.
- W2498903669 hasConceptScore W2498903669C119060515 @default.
- W2498903669 hasConceptScore W2498903669C126322002 @default.
- W2498903669 hasConceptScore W2498903669C203014093 @default.
- W2498903669 hasConceptScore W2498903669C2776042228 @default.
- W2498903669 hasConceptScore W2498903669C2776914184 @default.
- W2498903669 hasConceptScore W2498903669C2777014857 @default.
- W2498903669 hasConceptScore W2498903669C2778382381 @default.
- W2498903669 hasConceptScore W2498903669C2779394231 @default.
- W2498903669 hasConceptScore W2498903669C2779519742 @default.
- W2498903669 hasConceptScore W2498903669C2781195455 @default.
- W2498903669 hasConceptScore W2498903669C71924100 @default.
- W2498903669 hasConceptScore W2498903669C89560881 @default.
- W2498903669 hasConceptScore W2498903669C90924648 @default.
- W2498903669 hasIssue "2" @default.
- W2498903669 hasLocation W24989036691 @default.
- W2498903669 hasLocation W24989036692 @default.
- W2498903669 hasOpenAccess W2498903669 @default.
- W2498903669 hasPrimaryLocation W24989036691 @default.
- W2498903669 hasRelatedWork W2152173258 @default.
- W2498903669 hasRelatedWork W2366737289 @default.
- W2498903669 hasRelatedWork W2372049056 @default.
- W2498903669 hasRelatedWork W2390828669 @default.
- W2498903669 hasRelatedWork W2805778329 @default.
- W2498903669 hasRelatedWork W2892351422 @default.
- W2498903669 hasRelatedWork W2895944620 @default.
- W2498903669 hasRelatedWork W2897027559 @default.
- W2498903669 hasRelatedWork W3032298273 @default.
- W2498903669 hasRelatedWork W3160278422 @default.
- W2498903669 hasVolume "170" @default.
- W2498903669 isParatext "false" @default.
- W2498903669 isRetracted "false" @default.
- W2498903669 magId "2498903669" @default.
- W2498903669 workType "article" @default.