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- W2499040983 abstract "nometry, and esophageal pH monitoring, which are not performed routinely in patients with uncomplicated GERD symptoms. Even in those patients who are evaluated carefully, functional heartburn, as currently defined, would only apply to a small subset of endoscopy-negative patients. Given that patients with endoscopy-negative heartburn represent a combination of patients with acid related and non‐acid-related symptoms, the results reported in the systematic review by Dean et al. 4 in this issue of Clinical Gastroenterology and Hepatology are intuitively appealing. Their review found that patients with endoscopy-negative heartburn were significantly less likely than patients with erosive esophagitis to achieve a symptomatic response with proton pump inhibitors (PPIs) (erosive esophagitis 56% [95% confidence interval, 52%‐ 60%] vs. NERD 37% [95% confidence interval, 34%‐39%]). Several problems with the studies included in their systematic review deserve mention. No standardized definition for" @default.
- W2499040983 created "2016-08-23" @default.
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- W2499040983 date "2004-01-01" @default.
- W2499040983 modified "2023-09-27" @default.
- W2499040983 title "Erosive Esophagitis and NERD: Can We Really Classify Patients With Heartburn" @default.
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