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- W2499162875 abstract "Background: Consumers are using a number of alternative therapies for a variety of health issues. There is frequently no sound information discussing efficacy or toxicity upon which to base a sound decision regarding proposed therapies. Aim of the Study: To help address these concerns, a group of nutrients with potential efficacy in improving mental function was evaluated in a clinical setting. Material and Methods: A prospective, double-blind, randomized, placebo-controlled 3-month duration human clinical trial was performed to test a nutrient formulation for impact on parameters of mental function. Forty-one subjects were studied. Age ranged from 35-70 years. Two-thirds were from 40-60 years old which is considered middle age. This is a time when certain aspects of mental function decline. Subjects underwent baseline neuropsychological testing and were then randomized to receive placebo or active product. After three months, repeat testing was then performed and inter-group comparisons were analyzed. Results: Baseline profiles and neuropsychological test results were similar between groups. There was no toxicity associated with use of the nutritional formulation. Subjects receiving active product demonstrated statistically significant improvements on numerous clinical endpoints of the testing protocol. Conclusions: In this contingent of subjects, nutritional enhancement over a 3-month interval improved performance on various components of the brain testing protocol. This approach may be useful for functional mental enhancement during the mid-life period. The results need to be confirmed in a larger study." @default.
- W2499162875 created "2016-08-23" @default.
- W2499162875 date "2007-01-01" @default.
- W2499162875 modified "2023-09-26" @default.
- W2499162875 title "A Nutritionally Based Approach for Functional Mental Enhancement Assessment Using a Double-Blind, Placebo-Controlled, Randomized Clinical Trial" @default.
- W2499162875 doi "https://doi.org/10.5580/1a08" @default.
- W2499162875 hasPublicationYear "2007" @default.
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