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• W2499265265 abstract "Mitochondria contain 2 separate pathways for Ca 2+ transport. One is used for the uptake, and it consists of an electrogenic uniporter driven by the membrane potential generated by respiration, and inhibited by ruthenium red. The other route is used for the release of Ca 2+ , and has so far been identified and characterized in mitochondria from heart, brain, endocrine tissues, exocrine tissues, and skeletal muscles. It consists of a ruthenium red-insensitive system, which specifically exchanges Ca 2+ for Na + . In other mitochondrial types (liver, kidney, lung), the Na + -activated release route is absent. The available evidence, however, suggests separate pathways for Ca 2+ uptake and release also in these mitochondria. The simultaneous operation of the uptake and release routes results in the continuous cycling of Ca 2+ across the inner mitochondrial membrane." @default.
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• W2499265265 date "1980-01-01" @default.
• W2499265265 modified "2023-10-16" @default.
• W2499265265 title "THE CYCLING OF Ca2+ ACROSS THE INNER MITOCHONDRIAL MEMBRANE" @default.
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• W2499265265 doi "https://doi.org/10.1016/b978-0-08-023967-5.50053-x" @default.
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