Matches in SemOpenAlex for { <https://semopenalex.org/work/W2499286175> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W2499286175 endingPage "1151" @default.
- W2499286175 startingPage "1145" @default.
- W2499286175 abstract "The functions of peripheral blood monocytes in 14 untreated patients with lung cancer were examined before and after a 1-week course of OK-432 therapy(1 KE every day). The absolute monocyte count was calculated from the percent of monocytes in the total leukocyte count. The mean absolute numbers of monocytes before and after administration of OK-432 were 400/cmm and 437/cmm, respectively though the difference was not statistically significant. The lysosomal enzyme activity of monocytes was histochemically determined by betagalactosidase staining. The mean percentages of beta-galactoside positive monocytes before and after administration of OK-432 were 31.2 and 47.7 respectively. The increase was significant(P<0.05). The monocyte chemotactic response was measured in vitro by Boyden's millipore technique using zymosan activated human serum as the chemoattractant. The monocyte chemotactic responses before and after administration of OK-432 were 20.1 and 25.2, respectively and a significant difference was found between the two groups(P<0.01). The ability of monocytes to phagocytose complemented zymosan was accelerated by OK-432 administration, but the acceleration was not statistically significant. Cytostatic activities of monocytes on EBC-1 target cells before and after administration of OK-432 were 84.5 and 91.4, respectively the difference was significant(P<0.05). These results indicate that OK-432 activates the reduced monocyte functions in lung cancer patients in vivo, and that OK-432 may be a useful immunotherapeutic agent in man." @default.
- W2499286175 created "2016-08-23" @default.
- W2499286175 creator A5090797571 @default.
- W2499286175 date "1983-12-30" @default.
- W2499286175 modified "2023-09-28" @default.
- W2499286175 title "肺癌の免疫化学療法 第2編 免疫賦活剤(OK-432)の肺癌患者末梢血単球機能に及ぼす影響について" @default.
- W2499286175 hasPublicationYear "1983" @default.
- W2499286175 type Work @default.
- W2499286175 sameAs 2499286175 @default.
- W2499286175 citedByCount "0" @default.
- W2499286175 crossrefType "journal-article" @default.
- W2499286175 hasAuthorship W2499286175A5090797571 @default.
- W2499286175 hasConcept C126322002 @default.
- W2499286175 hasConcept C134018914 @default.
- W2499286175 hasConcept C150903083 @default.
- W2499286175 hasConcept C160448771 @default.
- W2499286175 hasConcept C16685009 @default.
- W2499286175 hasConcept C170493617 @default.
- W2499286175 hasConcept C185592680 @default.
- W2499286175 hasConcept C202751555 @default.
- W2499286175 hasConcept C203014093 @default.
- W2499286175 hasConcept C207001950 @default.
- W2499286175 hasConcept C2778870864 @default.
- W2499286175 hasConcept C2781184567 @default.
- W2499286175 hasConcept C3018023364 @default.
- W2499286175 hasConcept C54166955 @default.
- W2499286175 hasConcept C55493867 @default.
- W2499286175 hasConcept C71924100 @default.
- W2499286175 hasConcept C86803240 @default.
- W2499286175 hasConceptScore W2499286175C126322002 @default.
- W2499286175 hasConceptScore W2499286175C134018914 @default.
- W2499286175 hasConceptScore W2499286175C150903083 @default.
- W2499286175 hasConceptScore W2499286175C160448771 @default.
- W2499286175 hasConceptScore W2499286175C16685009 @default.
- W2499286175 hasConceptScore W2499286175C170493617 @default.
- W2499286175 hasConceptScore W2499286175C185592680 @default.
- W2499286175 hasConceptScore W2499286175C202751555 @default.
- W2499286175 hasConceptScore W2499286175C203014093 @default.
- W2499286175 hasConceptScore W2499286175C207001950 @default.
- W2499286175 hasConceptScore W2499286175C2778870864 @default.
- W2499286175 hasConceptScore W2499286175C2781184567 @default.
- W2499286175 hasConceptScore W2499286175C3018023364 @default.
- W2499286175 hasConceptScore W2499286175C54166955 @default.
- W2499286175 hasConceptScore W2499286175C55493867 @default.
- W2499286175 hasConceptScore W2499286175C71924100 @default.
- W2499286175 hasConceptScore W2499286175C86803240 @default.
- W2499286175 hasLocation W24992861751 @default.
- W2499286175 hasOpenAccess W2499286175 @default.
- W2499286175 hasPrimaryLocation W24992861751 @default.
- W2499286175 hasVolume "95" @default.
- W2499286175 isParatext "false" @default.
- W2499286175 isRetracted "false" @default.
- W2499286175 magId "2499286175" @default.
- W2499286175 workType "article" @default.