Matches in SemOpenAlex for { <https://semopenalex.org/work/W2499365789> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2499365789 endingPage "168" @default.
- W2499365789 startingPage "168" @default.
- W2499365789 abstract "OBJECTIVES: MicroRNAs are important modulators of the cellular epithelial-mesenchymal transition (EMT) process and are associated with metastasis in human nonsmall cell lung cancer (NSCLC). In this study, we tried to investigate the role of miR-338-3p in NSCLC cells. MATERIALS AND METHODS: Real-time polymerase chain reaction was applied to quantify the expression levels of miR-338-3p, as well as EMT-associated molecules in NSCLC cells. Wound healing and transwell assays were performed to evaluate the migration and invasion capacities, respectively. Dual-luciferase reporter assay was finally performed to determine the targeting of zinc finger E-box-binding protein 2 (ZEB2) by miR-338-3p. RESULTS: We found that miR-338-3p was significantly reduced in NSCLC cell lines. Forced expression of miR-338-3p in A549 cells led to the suppression of migration/invasion capacity and inhibition of epithelial markers. In addition, we proved that miR-338-3p could directly target ZEB2. CONCLUSIONS: In general, we summarized that miR-338-3p could inhibit EMT and metastasis of human NSCLC cells, which probably via directly targeting ZEB2 expression." @default.
- W2499365789 created "2016-08-23" @default.
- W2499365789 creator A5041669042 @default.
- W2499365789 creator A5085865763 @default.
- W2499365789 date "2015-01-01" @default.
- W2499365789 modified "2023-09-23" @default.
- W2499365789 title "miR-338-3p suppresses epithelial-mesenchymal transition and metastasis in human nonsmall cell lung cancer" @default.
- W2499365789 doi "https://doi.org/10.4103/0019-509x.186569" @default.
- W2499365789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27453416" @default.
- W2499365789 hasPublicationYear "2015" @default.
- W2499365789 type Work @default.
- W2499365789 sameAs 2499365789 @default.
- W2499365789 citedByCount "11" @default.
- W2499365789 countsByYear W24993657892017 @default.
- W2499365789 countsByYear W24993657892018 @default.
- W2499365789 countsByYear W24993657892019 @default.
- W2499365789 countsByYear W24993657892020 @default.
- W2499365789 countsByYear W24993657892021 @default.
- W2499365789 crossrefType "journal-article" @default.
- W2499365789 hasAuthorship W2499365789A5041669042 @default.
- W2499365789 hasAuthorship W2499365789A5085865763 @default.
- W2499365789 hasConcept C104317684 @default.
- W2499365789 hasConcept C121608353 @default.
- W2499365789 hasConcept C126322002 @default.
- W2499365789 hasConcept C137738243 @default.
- W2499365789 hasConcept C143998085 @default.
- W2499365789 hasConcept C145059251 @default.
- W2499365789 hasConcept C1491633281 @default.
- W2499365789 hasConcept C24284526 @default.
- W2499365789 hasConcept C2776256026 @default.
- W2499365789 hasConcept C2779013556 @default.
- W2499365789 hasConcept C502942594 @default.
- W2499365789 hasConcept C54355233 @default.
- W2499365789 hasConcept C55493867 @default.
- W2499365789 hasConcept C71924100 @default.
- W2499365789 hasConcept C76419328 @default.
- W2499365789 hasConcept C81729549 @default.
- W2499365789 hasConcept C86339819 @default.
- W2499365789 hasConcept C86803240 @default.
- W2499365789 hasConceptScore W2499365789C104317684 @default.
- W2499365789 hasConceptScore W2499365789C121608353 @default.
- W2499365789 hasConceptScore W2499365789C126322002 @default.
- W2499365789 hasConceptScore W2499365789C137738243 @default.
- W2499365789 hasConceptScore W2499365789C143998085 @default.
- W2499365789 hasConceptScore W2499365789C145059251 @default.
- W2499365789 hasConceptScore W2499365789C1491633281 @default.
- W2499365789 hasConceptScore W2499365789C24284526 @default.
- W2499365789 hasConceptScore W2499365789C2776256026 @default.
- W2499365789 hasConceptScore W2499365789C2779013556 @default.
- W2499365789 hasConceptScore W2499365789C502942594 @default.
- W2499365789 hasConceptScore W2499365789C54355233 @default.
- W2499365789 hasConceptScore W2499365789C55493867 @default.
- W2499365789 hasConceptScore W2499365789C71924100 @default.
- W2499365789 hasConceptScore W2499365789C76419328 @default.
- W2499365789 hasConceptScore W2499365789C81729549 @default.
- W2499365789 hasConceptScore W2499365789C86339819 @default.
- W2499365789 hasConceptScore W2499365789C86803240 @default.
- W2499365789 hasIssue "7" @default.
- W2499365789 hasLocation W24993657891 @default.
- W2499365789 hasLocation W24993657892 @default.
- W2499365789 hasOpenAccess W2499365789 @default.
- W2499365789 hasPrimaryLocation W24993657891 @default.
- W2499365789 hasRelatedWork W1637113035 @default.
- W2499365789 hasRelatedWork W1964681893 @default.
- W2499365789 hasRelatedWork W2014878562 @default.
- W2499365789 hasRelatedWork W2041752550 @default.
- W2499365789 hasRelatedWork W2092623911 @default.
- W2499365789 hasRelatedWork W2100044165 @default.
- W2499365789 hasRelatedWork W2255000697 @default.
- W2499365789 hasRelatedWork W2461728256 @default.
- W2499365789 hasRelatedWork W3150924289 @default.
- W2499365789 hasRelatedWork W4248542331 @default.
- W2499365789 hasVolume "52" @default.
- W2499365789 isParatext "false" @default.
- W2499365789 isRetracted "false" @default.
- W2499365789 magId "2499365789" @default.
- W2499365789 workType "article" @default.