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• W2499366867 abstract "Publisher Summary This chapter describes that tissue engineering is a strategy for the repair or replacement of damaged tissues or organs, involving the culture of living cells in vitro on a synthetic structure and the subsequent implantation of the construct into patients. It is termed, “morphogenesis.” The aim is to harvest a relatively small piece of tissue, to remove the cells, and then to expand the cell population. The cells can subsequently be re-implanted using a carrier material to assist in the generation of a substantial amount of tissue. Tissue engineering is a multidisciplinary area, which requires considerable biological input to gain insight into the behaviour of cells during in vitro culture and in vivo implantation. It also requires extensive engineering knowledge to fabricate and process materials that are suitable for guiding tissue development. Tissue-engineered constructs (TECs) are typically composed of two components: a group of cells and a material scaffold on which they can grow. Owing to the stringent requirements of tissue engineering, a number of key characteristics need to be met by the polymer. The chosen polymer must provide a biocompatible and biodegradable matrix with interconnected pores to ensure that the body tolerates the conduit and also promotes nutrient and cellular diffusion. The scaffold initially needs to provide mechanical stability and to act as a template to guide three-dimensional tissue growth." @default.
• W2499366867 created "2016-08-23" @default.
• W2499366867 creator A5047083527 @default.
• W2499366867 date "2007-01-01" @default.
• W2499366867 modified "2023-09-26" @default.
• W2499366867 title "Introduction to polymeric scaffolds for tissue engineering" @default.
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• W2499366867 doi "https://doi.org/10.1533/9781845693640.1" @default.
• W2499366867 hasPublicationYear "2007" @default.
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