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- W2499370672 abstract "Drug delivery systems capable of releasing active compounds in response to stimuli such as pH or temperature changes have attracted increasing interest in recent years. Among these systems, pH-sensitive liposomes have been studied extensively. These vesicles are generally stable at neutral pH and become leaky and/or fusogenic under acidic conditions. In this work, we describe the preparation of pH-sensitive phospholipid (liposomes) and non-phospholipid vesicles (niosomes) through the formation of pH-sensitive polymer/bilayer complexes. The vesicles are characterized with respect to their pH-sensitivity, stability in serum, pharmacokinetics and in vitro ability to deliver a model compound to the cytoplasm." @default.
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- W2499370672 date "2004-05-05" @default.
- W2499370672 modified "2023-10-18" @default.
- W2499370672 title "Stimuli-Responsive Liposome-Polymer Complexes" @default.
- W2499370672 doi "https://doi.org/10.1021/bk-2004-0879.ch002" @default.
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